ANTI-infective agentsANTIFUNGAL agentsMOUNTAIN soilsBackground: Vaginitis is a common infection in women, with approximately 75% of women experiencing at least one episode during their lifetime. Although antimicrobial agents are widely used to treat vaginitis, recurrent vaginitis occurs in ...
If an agreement on labeling can't be reached, FDA refers the issue to a pediatric advisory panel within the agency's Anti-Infective Drugs Advisory Committee, which has 90 days to review the label language and make any recommendations on label changes. Pediatric exclusivity law has a few new ...
IspC as Target for Antiinfective Drug Discovery: Synthesis, Enantiomeric Separation, and Structural Biology of Fosmidomycin Thia Isosters 来自 ACS 喜欢 0 阅读量: 72 作者: A Kunfermann,C Lienau,B Illarionov,J Held,T Gr?Wert,CT Behrendt,P Werner,S H?Hn,W Eisenreich,U Riederer 展开 摘要:...
Waksman in 1947 entitled “What Is an Antibiotic or Antibiotic Substance?” An antibiotic is a chemical substance, produced by micro-organisms, which has the capacity to inhibit the growth of and even to destroy bacteria and other micro-organisms. The action of an antibiotic against micro-...
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it was initially used as a medication against scabies, so its benefit as an anti-infective is well established. In this era of antibiotic resistance, there has been renewed interest in repurposing drugs as anti-infective, and disulfiram has been explored as a treatment for Staph infection, HIV...
However, these techniques are not yet automated and still rely heavily on the computational biologist's intuition. Molecular evolution and anti-infectives research seem to be an unlikely winning combination in today's competitive pharmaceutical environment. In practice, however, the application of ...
Drug-resistant fungal infections pose a significant threat to human health. Dual-targeting compounds, which have multiple targets on a single pathogen, offer an effective approach to combat drug-resistant pathogens, although ensuring potent activity and
135). Topical application of these substances circumvented challenges faced by an orally administered bacteriocin in the treatment of mastitis (n = 8) and acne vulgaris (n = 70), respectively. Given the increasing concerns presented by antibiotic-resistant strains of a variety of human ...