While there are other uses of ammonia, most (about 80%) of the industrially manufactured ammonia is used for fertilization purposes. Other uses of ammonia include its applications as a refrigerant and water purifying agent. Ammonia is also an important component while making explosives, other chemic...
Intriguingly, the large unstructured region encompasses two functional domains: a polar amino acid rich domain and a C-terminal domain. These findings suggest that PQBP-1 belongs to the family of intrinsically unstructured/disordered proteins. Furthermore, the binding of the target molecule U5-15kD...
. We hypothesize that the acquisition of caa3-type (A2-type) cytochrome c oxidase allows an efficient respiration ofUS. plumain this fully oxic environments. This cytochrome c oxidase is present in many aerobic bacteria and it has strong homology to the mitochondrial cytochrome oxidase (A1-type)...
5b). The 0 subsite is made up primarily of polar interactions (Fig. 5b). The axial O4 of the GalNAc (the unique difference of Gal versus Glc-configured substrates, the latter having an equatorial O4) coordinates with Oδ2 of D173 and NH1 of R174 (for further interactions see ...
one is near the gateway and three line the elongated hydrophobic tunnel. Consistent with the hypothesis that the gateway plays an important role in PL export, 25 of its 29 residues are 100% conserved in 34 species of ABCA1, from mammals to bony fish. Of the 53 amino acid residues that ...
Sequence analysis suggests that YhhN proteins contain eight transmembrane helices, an N-in/C-in topology, and about 5 highly conserved amino acid residues that may form an active site. This work is the first to demonstrate a function for a bacterial YhhN protein, as a vinyl ether bond ...
Vasa (Ddx4, DEAD box polypeptide 4), an extremely specific marker of germ cells in vivo, is an ATP-dependent RNA helicase that plays an essential role in germ cell development and gametogenesis. However, the expression and function information about this gene in groupers remains lacking. Here...
Tyrosine (Tyrosine; Tyr) chemical name for the 2 - amino - 3 - hydroxyphenyl propionic acid, it is a phenolic hydroxyl - containing aromatic polar α - amino acids. Tyrosine is a conditional essential amino acid and ketogenic amino acid. ...
Isavuconazonium sulfate is awater-soluble prodrug, which is rapidly hydrolyzed by esterases(mainly butylcholinesterase) in plasma into the active moietyisavuconazole (BAL-4815) and an inactive cleavage product(BAL-8728). Isavuconazole inhibits cytochrome P450 (CYP)-dependent enzyme lanosterol 14-a...
Amphiphilicity index of polar amino acids as an aid in the characterization of amino acid preference at membrane-water interfaces. Bioinformatics 18, 608–616 (2002). Article CAS PubMed Google Scholar Murga, M. et al. A mouse model of ATR-Seckel shows embryonic replicative stress and ...