AEG [N-(2-aminoethyl)glycine] is a small molecule which when polymerized can form a peptide nucleic acid backbone.Sandra Anne BanackJames S. MetcalfLiying JiangDerek CraigheadLeopold L. IlagPaul Alan Cox
glycine enolates6, glycinamides7, glycine Schiff's base8 and the aminohydroxylation of olefins9—the production of b-hydroxy-a-amino acids by enzymatic means is particularly attractive as these can set two stereocentres in a single reaction that can be performed in a one-pot process with ...
To address this, we examined the relative abundance of proteins across extraction types in the most enriched gene set: “small molecule catabolic process” (Fig. 5e). This revealed a complex interaction between extraction modality and metabolic protein abundance. Thus, metabolic protein carryover in...
Replacing the lysine or arginine residues with glycine within the described NoLS reduced the accumulation of proteins in the nucleolus (Fig. 2C and Supplementary Table S6). The replacement of two or three charged amino acids led to a stronger reduction in NoLS activity, and in general, the eff...
Creatine refers to a substance that gets produced in the muscle cells of our body. It involves a combination of amino acids L-arginine, L-methionine, and glycine. Most of this substance is produced naturally by our pancreas, kidney, and liver. Alternatively, they can also be sourced from pr...
2) the rate of α-synuclein polymerization in vitro decreases after the introduction of a single charged amino acid within these 12 residues, and a deletion within this region abrogates assembly; 3) this stretch of 12 amino acids appears to form the core of α-synuclein filaments, because it...
A recombinant soluble form of the IL-11Rα (sIL-11Rα) in combination with IL-11 acts as an agonist on cells expressing the gp130 molecule. We constructed a designer cytokine Hyper IL-11 (H11), which is exclusively composed of naturally existing components. It contains the full length ...
The product differed from the predicted native protein only by the addition at its amino terminus of a glycine and an alanine residue, which formed part of the target for speci®c proteolytic cleavage of the fusion protein. Two female rabbits were each initially immunized with 200 lg of ...
Structurally, the extracellular portion of Scl1 protein extends from the GAS surface as a homotrimeric molecule composed of distinct domains that include the most outward N-terminal variable (V) region and the adjacent collagen-like (CL) region composed of repeating GlyXaaYaa (GXY) sequence. The...
(UV15) and two copies of the fluorescent mNeonGreen protein joined with short glycine-based linkers.b, The Fionnbharth-MalO reporter phage contains 7 MalO (operator) binding sites for the transcription factor MalI. Each operator site can accommodate 2 MalI transcription factors for a total of ...