Resistance rates are increasing among several problematic Gram-negative pathogens that are often responsible for serious nosocomial infections, including Acinetobacter spp., Pseudomonas aeruginosa , and (because of their production of extended-spectrum 尾-lactamase) Enterobacteriaceae. The presence of multi...
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Bacterial resistance among Gram-negative pathogens is a challenging clinical problem. Tigecycline has been developed specifically to overcome resistance. T... R Naesens,JP Ursi,JVS Jeurissen - 《European Journal of Clinical Microbiology & Infectious Diseases》 被引量: 42发表: 2009年 加载更多来源...
After modification of these compounds into prodrugs for delivery into bacteria, we show that they kill clinical isolates of several multidrug-resistant bacteria—including those from the genera Acinetobacter, Pseudomonas, Klebsiella, Enterobacter, Vibrio, Shigella, Salmonella, Yersinia, Mycobacterium and ...
aNonfermenting Gram-negative Bacilli other than Pseudomonas aeruginosa and Acinetobacter Spp. Causing Respiratory Tract Infections in a Tertiary Care Center. 除绿浓杆菌和Acinetobacter Spp.之外的Nonfermenting革兰氏阴性的杆菌。 导致呼吸道传染在一个三重关心中心。[translate] ...
Acinetobacter baumanniiis a gram-negative nonfermenting bacterium that is found in humans, soil, meat, and vegetables.A. baumanniicause a variety of infections, including approximately 10% of nosocomial infections1,2,3. This is largely due to the acquisition or upregulation of plasmids, integrons,...
Acinetobacter baumannii is one of the most significant threats to global public health. This threat is compounded by the fact that A. baumannii is rapidly becoming resistant to all relevant antimicrobials. Identifying key microbial factors through which A. baumannii resists hostile host environment is ...
was found to act as a zinc ion sensor in the intestine and regulate individual feeding behaviour [126,127]. Zn2+is also used to promote the efficiency of antibiotics, such as vancomycin, quinolones, aminoglycosides, tetracycline, and macrolides [128]. For example, in gram-negative bacteria, ...
A nutrient-limited screen unmasks rifabutin hyperactivity for extensively drug-resistant Acinetobacter baumannii. Nat. Microbiol 5, 1134–1143 (2020). Article CAS PubMed PubMed Central Google Scholar Gopinath, K. et al. A vitamin B-12 transporter in Mycobacterium tuberculosis. Open Biol. 3, ...
For example, in Acinetobacter baumannii, we identify altered motility, biofilm formation, and interactions with the human immune system. Transposon capture is mediated by the DNA bridging activity of H-NS and, if absent, more ubiquitous transposition results. Consequently, transcribed and essential ...