Acetonitrile is a liquid with an etherlike odor. It is a highly polar, volatile solvent used in many different industrial applications. It is widely used in the pharmaceutical, photographic, chemical, and analytical industries. It is useful
To a solution of6-methoxy-3-methylindole(5.0 g,31 mmol) in distilled acetonitrile (150 mL) were added di- tert butyl dicarbonate(7.44 g, 34.1 mmol) andDMAP (0.195 g, 1.6 mmol).The reaction mixture was stirred at rt for 12 h. The solvent was removed underreduced pressure. The residue ...
0.33 mmol) inacetonitrile (10 ml) at room temperature, and the resulting mixture was stirredat room temperature for 2 h. Et 3 N (0.12 ml) was added and themixture was stirred at room temperature for 15 min. The solvents were removedin vacuo, and the residue was extracted with ethyl ace...
The solvent, which remains liquid to low temperatures, is a binary or higher order system comprising diethyl carbonate and one or more of propylene carbonate, ethylene carbonate, dimethyl carbonate, dipropylcarbonate, dimethylsulfoxide, acetonitrile, dimethoxyethane, tetrahydrofuran, n-methyl-2-pyrrolidone...
The solvent system consisted of 0.1% (v/v) trifluoroacetic acid in water (A) and 0.1% (v/v) trifluoroacetic acid in acetonitrile (B), and the sample was eluted with a linear gradient of 0–16% B over 30 min, with a flow rate of 1 mL/min. The products were detected by UV ...
(0.06% formic acid in acetonitrile) in 15 min. About 2.5 μl of the sample was injected into the column with an optimal flow rate of 400 µl/min. A diode array detector (UV/Vis DAD) was attached to the column, and the wavelengths of 230, 260, 280, 360, and 435 nm were ...
(I). In the nanoESI process, the types of Cu species and solvent were found to have a pronounced effect on the resulting mass spectra. When CuX (X = Cl, Br, or I) was dissolved into acetonitrile, comparable and intensive peaks of Cu-based ions appeared in the mass spectra (e....
The acetonitrile shortage: is reversed HILIC with water an alternative for the analysis of highly polar ionizable solutes? J Sep Sci. 2009;32(12):2001-7.PEREIRA A S, DAVID F, VANHOENZCKER G,et al.The acetonitrile shortage:is reversed HILIC with water analternative for the analysis of ...
The crude product was separated by preparative reverse phase chromatography using an Ascentis phenyl stationary phase and a gradient of the eluents (water/0.1% formic acid and acetonitrile/1% water/0.1% formic acid). Fractions containing compound-2 were combined, dried under reduced pressure and ...
When water is used as the filler, for example, an organic solvent may be used as a cosolvent; The liquefied gas diluent or carrier may include a liquefied gas diluent or carrier that exists in gaseous form at atmospheric pressure and temperature, for example, propane, nitrogen, carbon dioxide...