2 or Cl) is reacted with acetic anhydride into a novel compound of formula III; (2) this compound is solvolyzed under an acidic or basic condition into a second novel compound of formula IV; (3) this compound is condensed with 3,4-dihydro-2 H-pyran in the presence of an acid ...
However, pH 2 is not representative of the pH that CPPs may be exposed to when in contact with cells, either pH 7.2 outside the plasma membrane, or pH between 6.5 and 4.5 while inside acidic endosomes. In order to establish the relative hydrophobicities of d(X)TAT peptides at these ...
(e.g. concentrated sulfuric acid), methanesulfonic acid (e.g. anhydrous methanesulfonic acid) and the like); an acid anhydride such as acetic anhydride or trifluoromethane-sulfonic anhydride; P2O5 in methanesulfonic acid; a phosphorous-based halogenating agent such as P(O)Cl3, PCl3 or PCl5; ...