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DDX17 as a novel regulator of the DNA damage response pathway whose upregulation repairs defective DNA damage repair machinery caused by mutant neuronal FUS ALS. In addition, we show DDX17 is a novel modifier of FUS-mediated neurodegeneration in vivo. Our findings indicate DDX17 is downregulated ...
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cardiovascular risk factors have not been consistent. We examined the association of serum uric acid with all-cause mortality, ischemic stroke and myocardial infarction in a prospective population based study, with several traditional and non-traditional risk factors for cardiovascular disease included in...
Microvesicles from brain-extract-treated mesenchymal stem cells improve neurological functions in a rat model of ischemic stroke. Sci Rep. 2016. https://doi.org/10.1038/srep33038. Article PubMed PubMed Central Google Scholar Almeria C, Weiss R, Roy M, Tripisciano C, Kasper C, Weber V, ...
Daily ingestion of lead (Pb), even through piped drinking water, has long time been an important issue of concern, attracting for decades research in envir
An association between cognition and physical function has been shown to exist but the roles of muscle and brain structure in this relationship are not fully understood. A greater understanding of these relationships may lead to identification of the und
I am a physician-scientist, who prefers to do human clinical research. I have migrated to this position, in part, because I now question if animal-based research per se is predictive for the human being modeled [2, 8]. (See below for more on this.) I am writing this article because...
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