Cell Types Nucleus Histology Leukocytes NKT cells Nuclear envelope References Bargmann, W., Lindner, E., Andres, K. H.: Über Synapsen an endokrinen Epithelzellen und die Definition sekretorischer Neurone. Untersuchungen am Zwischenlappen der Katzenhypophyse. Z. Zellforsch. 77, 282–298 (19...
The brain consists of some 100 billion nerve cells (give or take a few bil- lion). Each cell is connected to thousands of other nerve cells in an astonishingly complex network. In scientific terms, the brain is sometimes called 'the final frontier,' because its function is still not ...
Data represent mean ± SEM, n = 5 mice per group Necroptosis is dispensable for motor neuron degeneration in a mouse model of ALS 1735 MLKL is expressed in peripheral organs, but not CNS tissues Given the lack of detectable MLKL levels in CNS tissues, we next determined the tissue ...
The podocytes (a key cell type that forms the interface between the blood and the urinary space) showed degenerative changes with effacement of the foot processes. When put together, these data show that lack of protection against endogenous formaldehyde leads to widespread DNA damage, causing two...
a denaturant-rich solution at 80 °C for at least 1 h (optimized time varies by tissue type; Supplementary Table1and Supplementary Note1) and observed crack-free expansion in mouse brain slices, a range of sectioned human tissues and human bronchial basal stem-cell-derived lung organoid...
For human tissue western blots, soluble protein fractions were used. Membranes were immunoblotted for phosphorylated c-AblThr735 (rabbit polyclonal, Cell Signal- ing Technology), total c-Abl (mouse monoclonal, clone 24–11, Santa Cruz Biotechnology), phosphorylatedSer/Thr- ATM/ATR protein targets ...
Optimized pipeline for cell profiling and TF detection In the present study, we first established a tissue processing pipeline for nuclear isolation followed by snRNA-seq. The nucleus suspension obtained with our protocol presented an intact morphology with few doublets/triplets (0.9–2.0%) (Supplement...
A neuron is a cell of the nervous system that is electrically excitable. Neurons have a very specialized cell shape, including a central cell body (or perikaryon), multiple short cell extensions called dendrites, a single long cell extension called the axon, and a swellin...
respectively. The graph presents the results of densitometry (n = 2 mice per tissue, sex and genotype). The intensity for each isoform band is expressed as a percent of the total intensity for each lane. Since there were no significant differences between values for male and female mice...
What neurotransmitter would be released by this neurone? Which of the 3 muscle tissue types would have multiple gap junctions? What muscles comprise the hamstring muscles? What are the two (2) neuron types whose cell bodies are in the spinal cord (CNS)? What is myelin? What type of cells...