Suspected low-grade glioma: is deferring treatment safe? Ann Neurol 1992; 31(4): 431-436.Recht LD, Lew R, Smith TW: Suspected low-grade glioma: is deferring treatment safe? Ann Neurol 31: 431–436, 1992Recht LD, Lew R, Smith TW. Suspected low-grade glioma: is deferring treatment ...
The dose–volume interaction in adult supratentorial low-grade glioma: higher radiation dose is beneficial among patients with partial resection Macdonald D , et al.The dose-volume interaction in adult supratentorial low-grade glioma: higher radiation dose is beneficial among patients with partial .....
There are various types of head tumors including gliomas, which are the most common type of malignant tumor. An acoustic neuroma is another type of head tumor, which is a tumor on the nerve in the head that leads to the inner ear. This type of tumor interferes with hearing and is usuall...
Nevertheless, gliomas are considered KRAS-driven cancers due to its essential role in mouse malignant gliomagenesis. Glioblastoma is the most lethal primary brain tumor, often associated with disturbed RAS signaling. For newly diagnosed GBM, the current standard therapy is alkylating ...
(R = 0.17,P < 2.2 × 10–16), including no positive correlation in low-grade glioma and glioblastoma (R = −0.11,P = 0.0023) (Extended Data Fig.4e,f). A gene expression correlation analysis of various human healthy organs revealed that SMARCD3 and DAB1 were ...
4I–K). These results underscore the association between ALKBH5 and glioma malignant phenotypes. Figure 4 The protein information of ALKBH5 in GBMs. (A) The immunofluorescence showed the protein distribution of the subcellular of GBM cells. (B) The immunohistochemistry data of GBM samples in ...
Behin A, Hoang-Xuan K, Carpentier A, Delattre J: Primary brain tumours in adults. The Lancet 361: 323–331, 2003 Article Google Scholar Maher E, Furnari F, Bachoo R, Rowitch D, Louis D, Cavenee W, DePinho R: Malignant glioma: genetics and biology of a grave matter. Genes Dev 15...
Thus, UA samples have superior cell yield and cover tumor heterogene- ity to a better extent than core biopsies. Results UA samples offer a greater source of viable cells compared to tumor core biopsies. In this work we have processed 40 UA samples from both low and high grade glioma,...
Although inhibition of glycolysis seems to be a logical approach to abrogating cancer metabolism and thus might selectively impact the malignant cells, so far, no clinically effective glycolytic inhibitors have been successfully developed for the treatment of cancer patients10. This is due in part to...
(Baylor College of Medicine). Prior to experimentation, the cryopreserved PDX tumor pieces were revived and surgically implanted in the mammary fat pad of a NOD/SCID female mouse for expansion for 5 weeks. PDX 7482 originated from a grade 3, stage 2 primary tumor, breast carcinoma [32]. ...