Hedgehog inhibition impaired platinum response in high-grade serous ovarian cancer harboring high hedgehog ligand expression and mTOR pathway activation. 5583 Background: Elevated Glioma-associated Oncogene Homolog-1 (Gli1) protein expression is associated with Hedgehog (Hh) pathway activation in high-...
- 《Journal of the National Cancer Institute》 被引量: 21发表: 1990年 Improved Treatment Efficacy of Antiangiogenic Therapy when Combined with Picornavirus Vaccination in the GL261 Glioma Model ImmunotherapyThe addition of antiangiogenic therapy to the standard-of-care treatment regimen for recurring ...
Glioma progression is regulated by the tumor microenvironment, which is mainly composed of tumor... Kaveri.Banerjee,Avinoam.Ratzabi,Itai M.Caspit,... - European journal of immunology 被引量: 0发表: 2023年 Multi-modality PET-CT imaging of breast cancer in an animalmodel using nanop article ...
In the 1920s, Otto Warburg observed that tumor cells consumed a large amount of glucose, much more than normal cells, and converted most of it to lactic acid. This phenomenon, now known as the “Warburg effect,” is the foundation of one of the earliest
tripled between 1997 and 2008, according to a report from Mount Sinai School of Medicine in New York. “国际儿童哮喘及过敏研究”(International Study of Asthma and Allergies in Childhood)是一项全球性的调查,其数据显示,1998年在发达国家中,只有约20%的孩子患有哮喘、过敏和疹子等过敏性疾病。纽约...
U Fischer,D Heckel,A Michel,... - 《Cancer Genetics & Cytogenetics》 被引量: 214发表: 1997年 Targeted disruption of the GAS41 gene encoding a putative transcription factor indicates that GAS41 is essential for cell viability. The glioma-amplified sequence (GAS) 41 protein has been proposed ...
MicroRNAs are strongly implicated in cancer but their specific roles and functions in the major cancers have yet to be fully elucidated. In this study, we defined the expression and function of miR-137, which we found to be downregulated in glioma samples and glioma cells by qRT-PCR. Ectopic...
If cancer is caused by mutations, so the reasoning goes, then maybe subtle patterns can be teased out of petabytes of bewildering cancer sequencing data. https://www.edge.org/response-detail/25380 J-Mac on December 25, 2019 at 6:02 pm said: Temozolomide Induced Hypermutation in Glioma: ...
Fetal cardiomyocytes actively proliferate to form the primitive heart in utero in mammals, but they stop dividing shortly after birth. The identification of essential molecules maintaining this active cardiomyocyte proliferation is indispensable for potential adult heart regeneration. A recent study has shown...
CACNA1C, as a type of voltage-dependent calcium ion transmembrane channel, played regulatory roles in the development and progress of multiple tumors. This study was aimed to analyze the roles of CACNA1C in ovarian cancer (OC) of overall survival (OS) an