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The novel allele of the LhMYB12 gene is involved in splatter-type spot formation on the flower tepals of Asiatic hybrid lilies (Lilium spp.) Tasaki, K., The novel allele of the LhMYB12 gene is involved in splatter-type spot formation on the flower tepals of Asiatic hybrid lilies (Liliu...
This report shows that the expression of spa (virulence gene encoding the cell-wall-associated protein A) is down-regulated by high osmolarity (1 M NaCl, 1 M KCl or 1 M sucrose) in the wild-type strain and upregulated by novobiocin (a DNA gyrase inhibitor that relaxes DNA). A gyrB142...
Answer to: Fill in the blank: An allele is said to be if it is not phenotypically expressed in the presence of another allele of the same gene. By...
By using CRISPR/Cas9 gene editing to target the region of alpha globin that interacts with eNOS (Fig. 4a), we generated a genetic model with a mutation (an in-frame deletion of 12 nucleotides, Fig. 4b, c) that removed Hba1 residues 36–39 (NH2–SFPT–COOH). We refer to this ...
While the human APOE gene has three common alleles, 𝜀2, 𝜀3 and 𝜀4, the APOE 𝜀4 allele is considered the most detrimental as it leads to an increase in AD risk and a decrease in the age of disease onset18,19,20,21. There have been great efforts to understand how APOE4 ...
Notably, the genetic variant with the largest effect size in the above-mentioned longevity genetic meta-analysis is the ε4 allele of the apolipoprotein E (APOE) gene [8]. The product of this gene plays a critical role in lipoprotein metabolism, with imbalances of the protein linked to ...
在SLC6A4基因上存在一个“5-羟色胺转运体基因连锁多态性区域”(5-hydroxytryptamine transporter-gene-linked polymorphic region),简称“5-HTTLPR”。所谓“多态性”就是同一基因的不同形态,也就是不同的等位基因。5-HTTLPR的DNA序列长度存在个体差异,有较短的“s”型和较长的“l”型。研究发现,s基因携带者(即...
Taken together, the abovementioned data suggest that intron 5 of CRYBB2 became fused with intron 5 of CRYBB2P1, resulting in a hybrid CRYBB2-CRYBB2P1 gene consisting of the first five exons and a part of intron 5 of CRYBB2 followed by the remainder of intron 5, exon 6, and the 3’...