www.nature.com/scientificreports OPEN received: 10 March 2016 accepted: 20 May 2016 Published: 13 June 2016 Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor Gregory M. Goldgof1,2,*, Jacob D. Durrant3,*, Sabine Ottilie...
YWHAE10 26 IVB YWHAE::NUTM2 Nanostringa 2.0 Disomy Disomy Weak and diffuse, n MX007 DOD 350 YWHAE11 70 IIIC YWHAE::NUTM2 NGS 14.3 Homozygous deletion Hemizygous and homozygous deletions Negative (50%) and strong and diffuse c + n (50%) MX007 DOD 219 YWHAE12 21 IIIC YWHAE::NUTM2 Na...
Table S1. Non-silent NF1 Mutations Identified by Sequencing Circulating Tumor DNA in a Metastatic ER + Breast Cancer Cohort, Related to Figure 1 Table S2. Multigene Proliferation Scores (MGPS) of Samples in the Z1031 Trial, Related to Figure 1 Table S3. E2 and 4-OHT Modulated Gene Express...
In this paper, we have considered human amniotic MSCs (hAMSCs) in the pathogenesis of PE as a source of PLACenta-specific protein 1 (PLAC1), an antigen involved in trophoblast proliferation. 1.1. The Oncogenic Theory of Preeclampsia: The Role of PLAC1 Antigen Genes of the gametogenic and/...
The microscope was controlled by Metamorph software (BioVision Technologies, Exton, PA, USA), which can stich single images together to obtain a view of a larger number of cells. 2.6. αENAC siRNA Knock-Down in Cells The hRTCs were plated in 6-well plates and grown to 50% confluent. ...
The entire set of diradicaloids is considered for the investigation of the relationship between intra-molecular reorganization energy, diradical character, and potential ambipolar electrical behavior. Based on the extended set of investigated diradicals, a simple two-dimensional representation of the PES...
2.2. Knockdown of EGLN1, a Gene Encoding a HIF1A-Degrading Protein HIF-PH, Resulted5ionf 14 Apoptosis of CLL Cells To further explain the good prognosis of CLL patients in the database with high ex- p2re.5s.siMonoliodfuHstIaFt1RAem, waiensfoEcfufescetidveoangaHinIFst-PIbHru, tainkieby...
energies Article Sucrose Is a Promising Feedstock for the Synthesis of the Platform Chemical Hydroxymethylfurfural David Steinbach 1,2,* ID , Andrea Kruse 2, Jörg Sauer 1 and Philipp Vetter 1 1 Institute for Catalysis Research and Technology, Karlsruhe Institute of Technology (KIT), Hermann-von...
The sites at positions −559 (TTCTCAGAA) and −1306 (CCCCCAGAA) of the BCL2L10 promoter showed a score of 0.97 and 0.98, respectively and hence were considered to be the most likely functional SRE in the human BCL2L10 gene. Thus, the region between −1674 to +115 of the ...