InsulinChristopher J.When a unit of insulin is not a unit:deter-mir dosing and insulin cost in type2diabetes mellitus. Insulin . 2009Johnson CK, Shimshi M. When a unit of insulin is not a unit: detemir dosing and insulin cost in type 2 diabetes mellitus. Insulin 2009; 4: 87-93....
1j). This may suggest that other insulin-sensitive tissues that may respond differently to the depletion of gut microbiota by ABX treatment, could also contribute to the whole-body insulin sensitivity, while the underlying mechanisms still need fine explorations. These results suggest that the gut ...
The third and fourth mammary gland pairs were removed from 8-week-old C3H female mice, minced thoroughly with scissors and digested in freshly prepared Digestion media containing DMEM/F12, 2 mg ml−1 Collagenase I (Roche), 5 ug ml−1 insulin (Sigma), 600 U ml−1 ...
Plasma lipids, blood glucose, insulin resistance and visceral fat quantity were not measured, which precluded analysis of any associations between prolactin and these CMD risk factors. Participants did not have particularly high risk factors for CMD, since they were normotensive and with mean BMI in...
Hypoxia-inducible factor 1-alpha HPA: Hypothalamic-pituitary-adrenal IGF: Insulin growth factor IL: Interleukin IR: Insulin resistance NC: Neck circumference NF-κB: Nuclear factor kappa-light-chain-enhancer of activated B cells NPSG: Nocturnal polysomnography OSA: Obstructive sleep apnea ...
1Citations Abstract Skin is a complex organ consisting of two very different tissue compartments, the epidermis and the dermis, which comprise cells of diverse origin and function. Establishing and maintaining the functionality of skin requires not only tightly regulated processes of maturation and diff...
This has been particularly true for the imprinted Insulin-like Growth Factor II (IGF2), a key regulator of embryonic growth in vertebrates and a focal point of the selective forces leading to genomic imprinting. The presence of the essential imprinting effector, DNMT3L, in marsupial genomes and...
Metformin, a type 2 diabetes treatment, improves the cognitive function of aged mice; however, whether the protective effects of metformin on cognitive function in aged mice are associated with the gut microbiome is poorly understood. Although some studi
Most of these correlated significantly with LTF, ADC and the perfusion data. Conclusions ADC and perfusion characteristics depend on breast density, which should be considered during the implementation of thresholds for malignant lesions. Dense and nondense breasts are two essentially different biological...
and impairment of insulin signaling54. On the other hand, BCKAs can allosterically inhibit BCKDH kinase (BCKDK) and thus alleviate the suppression of BCKDH activity by BCKDK, which in turn regulates the rate of BCAA metabolic pathway53. In this work, we demonstrate that besides BCAA catabolism...