关键词 : 藏鸡 ;IRX3 ;组织表达 ;时序表达 ;肌内脂肪 DOI :10.13560/j.cnki.biotech.bull.1985.2018-0048 Correlation Analysis Between IRX3 Gene Expression and Intramuscular Fat Deposition in Tibetan Chicken ZHANG Ya-nan LIN Ya-qiu XU Qing XU Ya-ou HE Qing-hua (College of Life Science and ...
Lifestyle intervention may have a critical effect on the association between genetics and obesity. This study aimed to investigate changes in FTO and IRX3 gene expression in obese and overweight male adolescents undergoing a lifestyle intervention and the role of FTO genotype in this interaction.This...
b, RT–qPCR analysis of proinflammatory gene expression in scWAT (a) and ATMs (b) of Irx3fl/fland Irx3fl/flLyz2Cremice housed at room temperature (RT; 22 °C) or 4 °C for 48 h (n = 5 for RT Irx3fl/fl, n ...
The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. Reference Data RefSeq NM_001253822, NM_008393 UniProt ID P81067 Synonyms AI894186 Summary Transcription factor involved ...
Storage Instruction Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. Applications Gene Info — IRX3 Diseases Related Products H00079191-B01P IRX3 MaxPab mouse polyclonal antibody (B01P) PAB30158 IRX3 polyclonal antibody H00079191-M11 IRX3 monoclonal antibody (M11...
Hoping to explain these observations, Nobrega and his team mapped the behavior of promoters -- regions ofDNA9thatactivate10gene expression -- located within one million base pairs on either side of the FTO gene. In adult mice brains, where FTO was thought to affectmetabolic11function, they dis...
Protein intake up-regulated the FTO gene (P = 0.001). In carriers of GG genotype of FTO gene, the amount of dietary carbohydrate had a positive association with FTO gene expression (p = 0.001, and p = 0.04, respectively). In AA/AG carriers, dietary protein was positively associated with...
Additionally, OR mice exhibited spontaneous WAT browning and less fibrosis, correlating with higher Irx3 expression. Utilizing 3T3-L1 differentiated adipocytes, our study demonstrated that overexpression of Irx3 promoted thermogenesis-related gene expression and reduced adipocyte fibrosis. Therefore, Irx3 ...
Conclusions : CAPN5 proteolysis of IRX3 influences its nuclear localization, and this may regulate expression of NIV-associated inflammatory genes.Joel Andrew FrancoMarcus ToralYoung Joo SunSoo Hyeon LeeGabriel VelezAlexander BassukVinit B Mahajan...
The researchers find one of the variants changes the binding ability of upstream regulator to IRX3/IRX5 and thus promotes IRX3/IRX5 expression instead of FTO. Which one is the real causal gene of common obesity, FTO, IRX3/5, both, or neither? All these questions need to be answered.(...