Moreover, the mean of depressive symptoms were 56.11 ± 7.30 and 48.55 ± 6.26 in the IBS and HC groups correspondingly. The results showed that the mean of anxiety and depressive symptoms were significantly higher in the IBS group compared to the HC group. While the HC anxiety...
In one aspect, the invention provides a method of reducing one or more symptoms of irritable bowel syndrome, by identifying a patient suffering from or at risk of developing irritable bowel syndrome, and administering to the patient a composition that includes Bacillus coagulans bacteria. Bacterial ...
This invention focuses on the development of compounds which are positive allosteric modulators of GABA-A receptors that are peripherally restricted, and their use in the treatment of disease. In some embodiments, the compounds of the present invention are useful in the treatment of irritable bowel ...
1980). Intensity of bowel symptoms is correlated with the so-called “motility index”, but no single or dominant feature helped to distinguish the subtypes. Severity of psychopathology is not correlated either with colonic motility or with seriousness of symptoms of IBS patients. Based on these ...