To examine whether this combined treatment is viable for use in vivo, the cytotoxicity of the combination of Fer and SnF2was assessed in immortalized human gingival keratinocytes (HGKs) using MTS assay. The cells were incubated with the combination of Fer (1 mg of Fe/ml) and SnF2(250 p...
we generated a rhodopsin gain-of-function cell line using the modelT. pseudonanabecause it lacks rhodopsin and, similar toF. cylindrus, is part of a broadly distributed genus.T. pseudonanawas selected overP. tricornutumfor testing the effect of recombinant expression ofFcR1 on...
Phylogenetic analysis demonstrated that SFXN2 is evolutionarily conversed from yeast to humans (Fig. 1a). SFXN2 proteins in vertebrates and invertebrates exhibit 70–91% and 44–56% similarity with human SFXN2, respectively. A previous in silico study demonstrated that fungal sideroflexin-1 (FSF...
He told her that now would not be the best time, as he wished to test him further. Wing insisted, saying that she wished not to lie to him anymore, to which her teacher replied that if he were to reject her after this, he was not right for her. ...
These compounds are detrimental to humans as they are known mutagens, carcinogens, and endocrine disruptors [10]. BTEX are easily transported to deep soil and groundwater due to their high solubility [11], thus affecting the groundwater quality and aquifer ecosystem. Therefore, it has become ...
Iron and zinc interactions in humans Am. J. Clin. Nutr, 68 (1998), pp. 442S-446S View PDFView articleCrossrefGoogle Scholar 2. Solomons N.W. Competitive interaction of iron and zinc in the diet: consequences for human nutrition J. Nutr, 116 (1986), pp. 927-935 View PDFView article...
Iron is essential to cells as a cofactor in enzymes of respiration and replication, however without correct storage, iron leads to the formation of dangerous oxygen radicals. In yeast and plants, iron is transported into a membrane-bound vacuole by the v
It is what we want to see, because humans tend to remember the very good things we’ve experienced in vivid detail while allowing the really bad experiences to fade. And yes, sitting here at my desk, I can close my eyes and imagine a cool fall day in Ft. Lauderdale, standing in ...
If data did not meet the assumptions after transformation, non-parametric tests such as the Wilcoxon test were used. The BH algorithm was used to correct p-values for multiple comparisons. Asterisks indicate significant differences between two groups: *p < 0.05; **p < 0.01; ***p ...
TfR1-mediated iron uptake by Treg cells is critical for the maintenance of immune tolerance To analyze the impacts of iron deficiency on regulatory T cells and immune tolerance, we specifically depleted TfR1 (coded by theTfrcgene), a major iron transporter, in Treg cells by crossingTfrcloxp/lo...