According to a previous study, a standard deviation of two points was to be expected [4]. For a two-tailed test (α = 0.05, power = 0.80) and anticipating a 10% dropout rate, we calculated a total sample size rounded to 140 participants. Analyses were by intention-to-treat. The null...
standard There are 2 proposed mechanisms to explain ION localization to sites of inflammation. Firstly, IONs passively migrate across the endothelium at sites of increased permeability or loss of endothelial integrity, such as sites of inflammation (19). IONs with smaller size have longer half-...
the usefulness of IV iron therapy increasingly is recognized in ACD as well as IDA.16,17 IV iron therapy, when given as an adjunct to ESA therapy, already is standard in dialysis- associated anemia of CKD.13,18 Accumulating evidence also sup- ports IV iron therapy in chemotherapy-induced an...
Descriptive statistics were determined, mean (x) as well as standard deviation (SD). The normality of distributions was verified with the Shapiro–Wilk test. Data distribution analysis was performed using parametric tests—the Student’st-test for dependent samples within the group and the same test...
Definition of ID based on the gold standard of bone marrow iron staining in heart failure patients. Circ. Heart Fail. 2018, 11, e004519. [Google Scholar] [CrossRef] [PubMed] Martens, P.; Dupont, M.; Dauw, J.; Nijst, P.; Herbots, L.; Dendale, P.; Vandervoort, P.; Bruckers,...
In thalassemia and sickle cell anemia, it is the standard treatment and can also be given to young children in regular blood transfusion. For these conditions, the producer recommends a slow subcutaneous infusion of a daily dose of 1000–2000 mg (20–40 mg/kg/day) which should be ...
The selection of change in peak V̇o2 for the primary end point, as previously described,15 was based on the fact that peak V̇o2 is the gold standard indicator of functional capacity in heart failure and has been shown to improve with iron repletion in non–heart failure populations. ...
Sera were stored at –20°C until assay in duplicate for prolactin concentration (mIU/L) using standard double-antibody RIA kits from ICN Pharmaceuticals, Costa Mesa, California. The assays were completed within 3– 4 y of collection. Inter-assay variability was 15% and the intra-assay ...
was higher than that of the gold-standard branched PEI. By establishing a tumor xenograft tumor model, the research results showed that the nanocomposites had good synergistic effects of PTT/gene therapy in inhibiting tumor cell proliferation, and promoting tumor cell apoptosis, which provided a new...
(P < 0.05) but was not greater than that of the PG (P > 0.05). The IG's serum ferritin (SF) was significantly increased on Days 20 and 28 (mean +/- standard error: 19 +/- 3 to 65 +/- 11 to 57 +/- 12 microg/L; P < 0.01), with a percentage change from baseline ...