Heart failure (HF) is commonly associated with iron deficiency (ID), defined as insufficient levels of iron to meet physiological demands. ID's association with anaemia is well understood but it is increasingly recognised as an important comorbidity in HF, even in the absence of anaemia. This ...
Influence of mitochondrial and systemic iron levels in heart failure pathology Heart Fail Rev, 24 (5) (2019), pp. 647-659 CrossrefView in ScopusGoogle Scholar 17 R.G. Tsushima, A.D. Wickenden, R.A. Bouchard, G.Y. Oudit, P.P. Liu, P.H. Backx Modulation of iron uptake in heart...
Myocardial iron homeostasis in advanced chronic heart failure patientdoi:10.1016/j.ijcard.2011.08.006HeartfailureIronAnemiaBackground Although, correction of iron deficiency and/or anemia in heart failure (HF) with iron seems promising, little is known about myocardial iron load and homeostasis. More...
heart failureiron deficiency anemiachronic kidney diseaseIron is an essential micronutrient for abounding physiological processes in the body, and its deficiency can be caused by various factors, such as low iron intake due to economic difficulties or loss of appetite, decreased iron absorption due to...
Sept. 25, 2024 – Nearly one-third of U.S. adults may have low iron levels that can add to problems ranging from fatigue to heart failure. Researchers in a new study estimated that 7% of U.S. adults have anemia, a blood disorder that can be iron-related and is particularly well-kn...
Inflammatory mediators such as interleukin-6 (IL-6) and bacterial-derived lipopolysaccharides (LPS) can directly trigger hepcidin production, leading to the retention of intracellular iron and decreased levels of iron in the circulation [4], [5]. Given that most extracellular pathogens appropriate ...
Iron deficiencyChronic Kidney Disease (CKD)Functional Iron Deficiency (FID)FID is present in one-fourth of our CKD cohort. It should be considered when ... BK Thapa,RK Mandal 被引量: 0发表: 2021年 Iron deficiency and supplementation in heart failure and chronic kidney disease Chronic kidney ...
hemoglobin levels; splenectomy status; systemic, hepatic, and cardiac iron overload indices; hepatic disease and infection studies; or iron chelator type. Pa... P Antonio,L Filomena,KM Musallam,... 被引量: 0发表: 2014年 Modulation of iron uptake in heart by L-type Ca2+ channel modifiers:...
Results: Chronic inflammation in HF, particularly in older adults, promotes functional ID through elevated hepcidin levels, impairing iron availability and worsening anemia. Current diagnostic criteria, relying heavily on ferritin, often misclassify ID due to inflammation. Intravenous (IV) iron therapy ...
ID in patients with advanced heart failure is not related to renal insufficiency. In our study, the results showed that there is not a statistically significant difference between creatinine of patients with ID (median 108 μmol/L) and without ID, where the levels were paradoxically slightly high...