This prospective investigation was aimed at examining iron status among blood donors with low circulating Hb and evaluating correlation between Hb values determined by capillary methods and those obtained by reference method from venous blood count (BC), as well as ferritin level. Methods. Between ...
serumferritin. A serum ferritin level greater than 100 ng/mL essentially rules outiron deficiency.8Other “classic” tests such as serum iron levels and transferrin saturation, have low predictive value. Increasedtotal iron binding capacityis specific, but not sensitive for early stages of iron ...
Evaluation of Iron Stores in Blood Donors by Estimation of Serum Ferritin level Context: Regular blood donation can lead to iron deficiency as well as iron deficiency anaemia. Screening of voluntary blood donor's serum ferritin levels at the time of donation is very important to estimate the iron...
Animals Thirteen dogs enrolled in a blood donor program donating ≥6 times over the preceding 12months and 20 healthy nondonor control dogs. Methods Prospective observational study. Mature red blood cell (RBC) indices, reticulocyte indices, serum iron, serum ferritin, and total iron-binding ...
Blood donor safety: Iron, citrate and moreK., Amrein
25.13). Intracellular iron regulates the level of IRPs. During the expansion of the iron pool, IRPs are inactivated, leading to efficient translation of ferritin mRNA and rapid degradation of transferrin receptor mRNA. In iron-replete cells, IRP1 acquires iron by the formation of iron–sulfur ...
The blood-donation experience: perceived physical, psychological and social impact of blood donation on the donor blood donation may be of great importance for the recruitment of new blood donors as it may make blood donation less frightening and perhaps even ......
In one study among patients with hereditary hemochromatosis, phlebotomy was associated with decreased hepcidin levels; although subjects’ hepcidin levels were low initially (van Dijk 2008; Galesloot 2011). Targeting a serum ferritin level slightly above the recommended range during maintenance phlebotomy ...
The level of excess iron in the body of iron-loaded patients can be diagnosed and monitored using a number of diagnostic techniques, most of which are also generally used for the monitoring of other diseases of iron metabolic imbalance. In addition to monitoring iron level parameters, regular cl...
At the systemic level, iron levels are regulated through the controlled absorption of dietary iron via enterocytes, duodenal cell sloughing, sweating, blood loss, and recycling of systemic iron [1,2]. At the cellular level, however, regulatory molecules such as ferroportin and hepcidin contribute ...