The dose range of IV iron was 100-300 mg, and patients received 2-5 infusions. Total doses were 400-1300 mg. 12/13 patients had an increase in hemoglobin. The median increase in hemoglobin was 1.7 g/dL. The median dose of iron that produced an increase in hemoglobin of one point ...
Among IV iron formulations administered, a total of 22 309 infusions (62.4%) were IS, 9011 (25.2%) were LMWID (of which 1715 [19.0%] were preceded by a test dose), 56 (0.16%) were test dose LMWID alone, 3147 (8.8%) were ferumoxytol, and 1214 (3.4%) were ferric ...
In 66–69% of US and European patients chronically treated with Epo injections for anemia, concomitant IV iron infusions are used to maintain marrow responsiveness, despite the evidence for accumulation of storage iron in tissues50,51. Mobilization of this storage iron paradoxically depends on ...
Immediately discontinue drug and obtain medical attention if symptoms of hypersensitivity or drug intolerance occur. Monitor patients for at least 30 minutes after completion of infusions. (See Dosage and Administration.)Cardiovascular EffectsPossible hypotension associated with IV administration; may be minim...
(4.3% of injections), but this difference was not statistically significant. The number of episodes ofperitonitisalso increased during the 6 months after intravenous iron infusion, especially with iron dextran, compared with the number of episodes during the 6 months before iron infusions, although ...
Conversely, after FC injection only half of the patients (4 out of 8) needed to continue oral supplementation and no further iv iron infusions were necessary. While receiving standard therapies, seven patients out of eight complained of asthenia; this symptom resolved in all cases after ferric ...
61 Over the next 10 years, the effectiveness of 24-hour infusions of IV62,63 and subcutaneous deferoxamine,64, 65 the efficacy and feasibility of 12-hour subcutaneous infusions,66 and the substantial fecal iron excretion induced by deferoxamine67 were reported. Together, these studies permitted ...
Current evidence from health economic analyses suggests that IIM can provide cost-savings to the healthcare system through lower resource usage (lower number of infusions per patient and a lower proportion of patients requiring multiple infusions) compared with other treatments [28,29,30,31]. Fewer...
In order to continue to live, they required regular infusions of fresh human genetic material acquired by an agonisingly fatal extraction process, and from their base upon a barren, ravine-hollowed moon known as the "Rock of Judgement," they held sway over a dozen nearby human-inhabited worlds...
Drug-specific hypophosphatemia and hypersensitivity reactions following different intravenous iron infusions. Br J Clin Pharmacol. 2017;83:1118–25. https://doi.org/10.1111/bcp.13189. Article PubMed PubMed Central CAS Google Scholar Mulder MB, van den Hoek, Hester L, Birnie E, van Tilburg, ...