Portable infusion pumps used to administer 24-h subcutaneous infusions 1976 64, 65 12-h infusions calculated to achieve iron balance 1978 64 Long-term subcutaneous therapy reduces hepatic iron concentration 1981 98, 99 Significant fecal iron excretion induced by deferoxamine 1982 66 Long-term subcutan...
Aim of this study was to evaluate whether the A736V TMPRSS6 polymorphism, a major genetic determinant of iron metabolism in healthy subjects, influences serum levels of hepcidin, the hormone regulating iron metabolism, and erythropoiesis in chronic hemodialysis (CHD). Methods To this end, we conside...
Iron poisoning is a well-respected historically significant toxicologic problem. In the pediatric population, iron has been regarded as the most fatal of all toxic exposures [1]. Fortunately because of regulations on packaging in the USA and other countries, serious poisonings have declined [2]. ...
Iron deficiency is the commonest nutritional deficiency disorder prevalent worldwide. It is the main cause of anemia during pregnancy and lactation among women and infancy and preschool age in children. In the developing countries, the prevalence is usua
Serum gallium levels of 0.115 and 0.569 μg/ml have been achieved following a single oral dose of 100–500 mg gallium maltolate; this is comparable to steady-state levels achieved with gallium nitrate administered by continuous intravenous infusion [110]. The majority of gallium appearing in the...
Patients received ferric carboxymaltose (FCM), a recent formulation of intravenous iron, allowing higher doses and rapid infusion times. Following FCM infusion as a single dose of 15 mg/kg up to 1000 mg over 15–20 min, 64% of patients with IDA had resolution of anemia, with 81% ...
The deferoxamine group had the study infusion prepared in such a way as to deliver a total dose of 13.3 mg/kg bw, which was added to 0.9% w/v NaCl (Sodium chloride 0.9% IV Infusion, Baxter Healthcare Pty Ltd., Toongabble, NSW, Australia) to bring the total volume for infusion to...
Iron chelation using subcutaneous infusion of diethylene triamine penta-acetic acid (DTPA). Scand. J. Haematol. 1986, 36, 466–472. [CrossRef] [PubMed] 28. De Virgilis, S.; Cognia, M.; Turco, M.P.; Frau, F.; Dessi, C.; Argiolou, F.; Sorcinelli, R.; Sitzia, A.; Cao, ...
maltophilia strains (see Table 1), revealed the presence of shared iron acquisition and metabolism subsystems, with an additional system in some S. maltophilia strains. The subsystem information, generated through the Rapid Annotations using Subsystems Technology (RAST) server, is included in ...
Current protocols for the optimization of iron excretion caused by deferoxamine in thalassaemia and other transfusional iron loaded conditions involve the oral administration of a total of 400 mg; 200 mg before and 200 mg during the subcutaneous infusion of deferoxamine. Different mechanisms are ...