(2004) Liver iron deposits in hepatitis B patients: association with severity of liver disease but not with hemochromatosis gene mutations. J Gastroenterol Hepatol 19: 1036-1041.Martinelli, AL, Filho, AB, Franco, RF (2004) Liver iron deposits in hepatitis B patients: association with severity ...
Background and Aims: Iron deposits in the liver and abnormalities in serum iron biochemistry are frequently observed in patients with chronic liver diseases, but data for patients with hepatitis B virus (HBV) infection are scarce. Moreover, the role of HFE mutations in iron deposits in this con...
Nuclear deposits of stainable iron in hepatocytes are a sign of liver iron overload in mice. Animals with no, partial or total knock-out of the HFE alleles, the deletion of which is responsible for hereditary haemochromatosis, were given different forms of dietary iron to measure nuclear iron...
Chronic liver disease decreases the synthetic functions of the liver, including the production of hepcidin, a key protein in iron metabolism. Lower levels of hepcidin result in iron overload, which leads to iron deposits in the liver and higher levels of non-transferrin-bound iron in the ...
Effects of HyMF and HyMF+HLU on iron distribution in tissues of mice. Histological analysis of iron deposits in liver (A, Bar=20 μm), spleen (C, Bar=50 μm) and duodenum (E, Bar=20 μm) sections by Perls' iron staining. Atomic absorption spectrometry detected the total iron conten...
The affected heart has a rusty brown, hypertrophiedleft ventricle(Figure 11.36a). The histological appearance of iron storage on hematoxylin-eosin-stained sections is that of intramyocytic granular brownish deposits (Figure 11.36b), which are blue on a pink field byblue Prussian(Perls) staining ...
This iron is dispersed in various organ systems: approximately 65% and 75% are bound to circulating hemoglobin, 22% and 12% are deposited in liver (ferritin and hemosiderin), and 2.9% and 4.6% are bound to various enzymes. For both sexes, approximately 10% of iron is coupled with ...
Additional studies showed that Ndfip1−/− mice have increased iron deposits in their livers16 and that Ndfip1 is important for DMT1 regulation in the duodenum under low iron conditions18. However, the in vivo role for Ndfip2 has not been investigated. To determine the importance of ...
Mssbauer spectroscopic study of iron oxide deposits in liver tissue from the marine mammal Dugong dugong A sample of liver from the marine mammal Dugong dugong was found to have an iron concentration of 137 000 螠g g 1 Fe dry weight. Histological examination of the tissue revealed dense extrac...
The relation between serum ferritin levels and stainable-iron deposits in the liver, spleen, and bone marrow was investigated in 36 patients with chronic r... M Ali,A Olusegun Fayemi,J Frascino,... - 《Lancet》 被引量: 235发表: 1982年 Early prediction of response to intravenous iron ...