iron‐deficiency anemiadecompensationBackground and aim: Iron deficiency anemia (IDA)is the leading cause of anemia worldwide. Data on prevalence and clinical impact of anemia in cirrhosis are scarce. Aim was to report on the following:(i) prevalence of anemia and IDA in cirrhosis and (ii) ...
Iron overload can cause oxidative stress and lipid peroxidation, and can, for example, increase the formation of intracellular lipid droplets in liver cells in vitro. Conversely, iron deficiency has been shown to increase lipogenesis in rat liver, resulting in triglyceride accumulation and steatosis11...
Iron Deficiency Anemia burden Anaemia affects approximately 430 million people aged 10-24 worldwide, withlow- and middle-income nations seeing the highest rates.As the years between childhood and adulthood represent a sensitive period for developmental, physiological andbehavioralchanges,anemiain ...
Iron metabolism is a tightly regulated physiological process that has relatively low redundancy, and its deregulation often leads to iron deficiency or iron overload. Iron deficiency and iron overload are historically associated with erythroid disorders; however, deregulated iron metabolism is also implica...
As well as iron-only types, most multivitamin and mineral supplements, as well as prenatal supplements, often contain iron. Read more:What Are the Best Iron Supplements for Women? Do You Need a Supplement? Certain conditionsmay put you at risk for developing a deficiency in iron and...
Umbreit, J. Iron deficiency: a concise review.Am. J. Hematol.78, 225–231 (2005). ArticleCASPubMedGoogle Scholar Schaible, U. E. & Kaufmann, S. H. Iron and microbial infection.Nature Rev. Microbiol.2, 946–953 (2004). ArticleCASGoogle Scholar ...
Methylphenidate improves cognitive deficits produced by infantile iron deficiency in rats. Behavioural Brain Research, 2011, 216(1): 146-152. [3] M. B. Youdim. Brain iron deficiency and excess; cognitive impairment and neurodegeneration with involvement of striatum and hippocampus. Neurotoxicity ...
DominiqueBouglé, inTea in Health and Disease Prevention, 2013 Iron Deficiency In most cases, however, iron is not in excess but deficient.Iron deficiencymay concern only storage (decrease of ferritin); a higher degree of deficiency leads toiron deficiency anemia. The main consequence of iron de...
Iron imbalance in cancer: Intersection of deficiency and overload. Cancer Med. 2022, 11, 3837–3853. [Google Scholar] [CrossRef] Vassiliou, E.; Farias-Pereira, R. Impact of Lipid Metabolism on Macrophage Polarization: Implications for Inflammation and Tumor Immunity. Int. J. Mol. Sci. 2023...
This duality is found in human pathology: Iron deficiency (because of poor iron intake, abnormal blood losses etc...) presents with anemia and fatigue; whereas iron overload (mainly in hereditary hemochromatosis and following repeated blood transfusions) induces multiple organ dysfunctions (including ...