Iron is essential for life, but iron overload is toxic and potentially fatal. The liver is a major site of iron storage and is particularly susceptible to injury from iron overload, especially when (as in primary hemochromatosis) the iron accumulates in hepatocyte...
The liver is held to play an important part in the regulation and excretion of the serum Fe. This function is disturbed in catarrhal jaundice and the Fe content of the blood rises. There is a retention of Fe in other types of jaundice also. The role of the colon in the excretion of ...
The same tests were not significantly different when black and nonblack women were compared. Likely causes of the laboratory abnormalities are occult inflammation and occult liver disease, but a primary disorder of iron metabolism is also possible. 展开 ...
Iron plays a pivotal role in adult steatosis, but its role in child and adolescent steatosis is unclear. We investigated the effect of dietary iron, serum iron, and ferritin on serum transaminases and γ-glutamyltransferase in 10- and 13-year-olds.The study included 4894 fifth and eighth grade...
The dysmetabolic iron overload syndrome (DIOS) is now a frequent finding in the general population, as is detected in about one third of patients with nonalcoholic fatty liver disease (NAFLD) and the metabolic syndrome. The pathogenesis is related to altered regulation of iron transport associated...
Reduction of has been reported both in patients and in animal models. We have measured liver and other gene transcripts in two different models of at different ages. DESIGN AND METHODS: (th/th), characterized by spontaneous homozygous deletion of the major b1 gene were studied at 2 and 8 ...
Measurement of liver iron concentration (LIC) is necessary for a range of iron-loading disorders such as hereditary hemochromatosis, thalassemia, sickle cell disease, aplastic anemia, and myelodysplasia. Currently, chemical analysis of needle biopsy specimens is the most common accepted method of measur...
摘要: SUMMARYThe mean iron content of finger-nails of 113 apparently normal subjects was found to be 67.6 μg/g dry nail (±43.7). There was no age or sex variation. No relationship was found between the concentration of iron in finger-nails and that stored in the liver....
How to use Liver, Iron, And Vitamins Tablet Take this medication by mouth, usually once daily or as directed. Follow all directions on the product package, or take as directed by your doctor. Do not take more than the recommended dosage. If you have any questions, ask your doctor or pha...
Liver injury was assessed by the leakage of cytosolic enzymes, AST and LDH, into the perfusate. Livers perfused at 42°5°C showed significant rises (p < 0°05) in AST and LDH after 60 min of perfusion but perfusion at 42°5°C with deferoxamine added, was not significantly different ...