However, chromatin immunoprecipitation–PCR analyses of Aiolos binding near the transcriptional start site of c-Myc or IRF4 resulted in very few binding events (<4) compared with other target promoters (data not shown). Alternatively, it is possible that Ikaros and Aiolos negatively control the ...
Core Patent Clinical Trial Approval Regulation Overview Basic Info Drug Type Monoclonal antibody Synonyms Anti-CD38 monoclonal antibody(Sanofi),Isatuximab,Isatuximab (Genetical Recombination) + [8] Target CD38 Mechanism CD38 inhibitors(Lymphocyte differentiation antigen CD38 inhibitors),ADCC(Antibody-dependent...