In our studies, we show that lenalidomide or pomalidomide could effectively target the c-Myc/IRF4 axis, and that once that axis is compromised, MM cells can no longer be rescued from growth inhibition (Figure 4). In addition, our results and those of others7, 8, 9, 17 suggest that ...
Target CD38 Mechanism CD38 inhibitors(Lymphocyte differentiation antigen CD38 inhibitors),ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects),Apoptosis stimulants Therapeutic Areas NeoplasmsImmune System DiseasesCardiovascular Diseases+ [3] ...