在HLA领域内,术语“等位基因”指的是点突变、插入和删失的组合,因此,与单个参考序列相比,每个等位基因可以由多个不同的变异位置组成。这些等位基因信息储存在IPD-IMGT/HLA数据库中。IPD-IMGT/HLA 数据库(https://www.ebi.ac.uk/ipd...
IPD-IMGT/HLA is a constituent of the Immuno Polymorphism Database (IPD), which was developed to provide a centralised system for the study of polymorphism in genes of the immune system. The IPD project works with specialist groups of nomenclature committees who provide and curate individual sectio...
Streamlining submission to the IPD-IMGT/HLA database: The sequence feature annotation tooldoi:10.1016/j.humimm.2024.110918D.J. BarkerR. NatarajanJ. RobinsonS.G. MarshHuman Immunology
The IPD-IMGT/HLA Database, http://www.ebi.ac.uk/ipd/imgt/hla/, currently contains over 25 000 allele sequence for 45 genes, which are located within the Major Histocompatibility Complex (MHC) of the human genome. This region is the most polymorphic region of the human genome, and the ...
c alignments; however, we are working to allow crossspecies alignments and the inclusion of human sequences from the IMGT/HLA database (12) for comparative purposes. The IPD-MHC Sequence Databases will also contain a submission tool for online submission of new and con?rmatory sequences to ...
1111/j.1399-0039.2010.01466.x Robinson J, Waller MJ, Parham P et al (2003) IMGT/HLA and IMGT/ MHC: sequence databases for the study of the major histocompati- bility complex. Nucleic Acids Res 31:311–314 Robinson J, Waller MJ, Stoehr P, Marsh SGE (2005) IPD—the immuno ...
The system was modeled on the IPD-IMGT/HLA database but expanded to cover multiple species and nomenclature systems. The initial release contained data on non-human primates, felines, and canines. Since this time, further data on horse, sheep, swine, cattle, fish, and rats have been added...
Along with the Immuno Polymorphism Database-IMunoGeneTics/human leukocyte antigen (IPD-IMGT/HLA) database, a collection of databases for curated sequences of immune importance has been developed. A recent addition is an IPD-MHC database for chickens. For many years, the nomenclature system for ...
The IPD-MHC Database was released in 2003 to provide a curated database of MHC sequences from a number of non-human species. The system was modeled on the IPD-IMGT/HLA database but expanded to cover multiple species and nomenclature systems. The initial release contained data on non-human...
The IPD-IMGT/HLA Database - New developments in reporting HLA variation. IPD-IMGT/HLA is a constituent of the Immuno Polymorphism Database (IPD), which was developed to provide a centralised system for the study of polymorphism ... J Robinson,AR Soormally,JD Hayhurst,... - 《Human Immuno...