In neurons and other excitable cells, regulation of the ionic environment is also crucial for the development and maintenance of the specific signaling pathway for these cells, known as the electrical signaling system . This system is composed of two basic elements: i) a lipid bimolecular ...
Cancer cells tend to be depolarized (low membrane potential in absolute value), which has been connected with overexpression of specific ion channels27. In particular, upregulation of sodium channels and downregulation of potassium channels has been ascribed to carcinoma cell lines and tissues7. The ...
Bioelectric controls of cell proliferation: ion channels, membrane voltage and the cell cycle. All cells possess long-term, steady-state voltage gradients across the plasma membrane. These transmembrane potentials arise from the combined activity of ... DJ Blackiston,KA Mclaughlin,M Levin - 《Cell...
Ion Channels in the Modeling of Multicellular Patterns and Cancer Biophysics Javier Cervera1, Antonio Alcaraz2 & Salvador Mafe1 Bioelectrical signals and ion channels are central to spatial patterns in cell ensembles, a problem of fundamental interest in positional information and cancer processes...
However, the interactions between ion channels and cancer-related signaling pathways are poorly understood so far. Nevertheless, a limited number of reports have recently addressed this important issue, especially regarding the interaction between ion channels and one of the main driving forces for ...
- 《Science Signaling》 被引量: 104发表: 2009年 A Small Fraction of Strongly Cooperative Sodium Channels Boosts Neuronal Encoding of High Frequencies is coordinated only through the transmembrane potential.However, biological ion channels of various types can exhibit strongly cooperative gating when ...
Channels involved in migration are frequently regulated by Ca(2+) signaling, most likely coupling extracellular stimuli to cell migration. Importantly, the inhibition of ion channels and transporters appears to be clinically relevant for the treatment of cancer. Recent preclinical data indicates that ...
Calcium-permeable ion channels in pain signaling The detection and processing of painful stimuli in afferent sensory neurons is critically dependent on a wide range of different types of voltage- and liga... E Bourinet,C Altier,ME Hildebrand,... - 《Physiological Reviews》 被引量: 0发表: ...
网络离子通道 网络释义 1. 离子通道 ...:为细胞内重要的酵素,一旦被自由基破坏,造成细胞的离子通道(Ion-Channels)出现问题,令到细胞内钙离子失去平衡,钙… www.healthwise.com.hk|基于 1 个网页 例句 释义: 全部,离子通道 更多例句筛选
Cell Signaling Tools Cl- Channels Cyclic Nucleotide-Gated Cation Channels Diabetes Epilepsy Epithelial Cell Membrane Proteins Gap Junction Channels H+ Channels Hyperpolarization-Activated Cation (HCN) Channels Intracellular Ion Channels K+ Channels Ligand-Gated Ion Channels Lysosomal Ion Cha...