Evaluation of gland function is best accomplished via a scintigraphic examination with the intravenously introduced radioisotope, technetium-99 m pertechnetate (TPT). The TPT, a radioisotope of molybdenum, is considered safe because it only has a 6-hour half-life and does not produce any destructiv...
S3). The half-maximal inhibitory concentration (IC50) was calculated by curve fitting (Fig. 6A). We confirmed the effect of ZY-444 on PC activity and showed that ZY-444 significantly reduced PC activity in PTC cells at a concentration of 1 µM (Fig. 6B). Scratch wound assay and ...
Volatile and radioactive iodine species (e.g., 129I and 131I) possess exceptional issues, mainly because 129I has a very long half-life (~107 years) and 131I has direct effects on human metabolic processes despite its short half-life (8.02 days). Therefore, efficient capture and reliable...
Since life expectancy is high and DTC is very common in persons younger than 55 years of age, these patients have increased morbidity from treatment- related side effects without clear benefit. The side effects of I-131 ablation can be acute or chronic and include sialadenitis, nasolacrimal ...
Choice of isotope: for iodine, this lies between the sodium salts of 131I and 125I. In current practice, the latter is recommended for the following reasons: (a) the half-life is greater (60 days as against 8 days) so that the shelf-life of the tracer is potentially greater ; (b)...
(Electronic Supplementary Information, ESI). Half life time of131I is 8.02 days, and131I subsequently transforms into radioactive131Xe in the form of gas, and it may be released from the PANI [15]. Therefore, PANI as a131I absorber can be valid in short term application for the ...