A Screen for Genes Involved in Cell Division in Caenorhabditis elegans Cell division and membrane trafficking are crucial processes for all cells. Membrane trafficking is important during cell division in both plant and animal... K Waukau,AR Skop,DS Poole - 《Cbe.wisc.edu》 被引量: 0发表: ...
as it is most vulnerable to ischemia. However, this region is also involved in renal tubular regeneration. To deeply understand the mechanism of the repair process after ischemic injury in AKI, we focused on glial cells missing 1 (Gcm1), which is one of the genes expressed in the ...
Mutated APC and ASEF are involved in the migration of colorectal tumour cells. Nat Cell Biol. 2003; 5 :211–215. doi: 10.1038/ncb937. [ Cross Ref ]Kawasaki Y, Sato R, Akiyama T. Mutated APC and Asef are involved in the migration of colorectal tumour cells. Nat Cell Biol. 2003; 5 ...
The primary objective of this study was to identify and analyze genes that play crucial roles in the complicated cascade or network for induction of meiotic division to produce the gametes in almost all multicellular organisms at the final step of formation of their germ cells. In gynogenetic ...
Sponge immunocyte identification is of interest to comparative immunologists since characterizing these cells will allow investigations into the mechanisms of non-self recognition in the oldest animal phylum. Here, we report that polyclonal antibodies raised against the core protein of a proteoglycan invol...
Altogether, these results show that RNAi of polg-1 and mtss-1 over one generation lead to a specific knockdown of polg-1 and mtss-1, to a severe mtDNA depletion in somatic cells but does not result in major anomalies in worms development. 2.2. Ethidium bromide exposure combined with polg-...
Soil contaminated with the heavy metal Cadmium (Cd) is a widespread problem in many parts of the world. Based on metagenomic analysis, we investigated the functional potential and structural diversity of the microbial community in Cd-contaminated and non-contaminated soil samples and we explored the...
To provide functional validation, we knocked out Slit2, Atxn1, and Cdkn2a in mouse tumor organoids and transplanted to mice. Tumor development was promoted when these gene were knocked out, demonstrating that these are potent tumor suppressors. Cdkn2a knockout cells also metastasized to the liver...
in the proband and his sibling, which had irregular flagella and aberrant heads (Fig.1aand Supplementary Fig.1a). Similar clear features were also observed in the sperm cells from the two siblings by scanning electron microscopy (SEM) (Fig.1b). In addition, transmission electron microscopy (...
In this study, we examined the roles of sphingomyelin synthase (SMS) in HIV-1 Env-mediated membrane fusion using a cell-cell fusion assay with HIV-1 mimetics and their target cells. We employed reconstituted cells as target cells that stably express Sms1 or Sms2 in Sms-deficient cells. ...