We found a similar spine maturation defect upon overactivation of inverted formin 2 (INF2), a nucleator of unbranched F-actin with hitherto unknown synaptic function. While INF2 overactivation failed in altering spine density or morphology in CAP-deficient neurons, INF2 inactivation largely rescued...
INF2Mutations in the gene encoding inverted formin FH2 and WH2 domain-containing protein (INF2), a Cdc42 effector involved in the regulation of actin dynamics, cause focal segmental glomerulosclerosis (FSGS) and intermediate Charcot-Marie-Tooth neuropathy combined with FSGS (FSGS-CMT). Here, we...
Inf. Process. Syst. 25, 1097–1105 (2012) MATH Google Scholar Szegedy, C., Ioffe, S., Vanhoucke, V., Alemi, A.: Inception-v4, inception-resnet and the impact of residual connections on learning. In: Proceedings of the AAAI Conference on Artificial Intelligence, vol. 31, pp. 4278...
Each capsule in this layer represents a possible category, and by calculating the activation level of each capsule, the probability of the input text belonging to which category can be determined, which is used to form capsules representing categories: $$\begin{aligned} {\textrm{Y}} = [{y_...
Various functions that possess these characteristics are examined using the least-squares fitting method in order to determine whether they can predict the experimental results well. Finally, it is found that the measurement results are predicted best when the functional form is: NuL = C1(RaH Ac/...
In classical mechanics, it is equivalent to Newton's laws of motion, but it has the advantage that it takes the same form in any system of generalized coordinates and it is better suited to generalizations. For the purpose of modeling, the RDIP works as follows. The movement of the arm ...
(1 + ml2)0 + mgl sin = —nilxcos 9 u to represe nt the con trolled object with the in put force F, li nearized two moti on equati ons Apply Laplace tran sform to the equati on above + 心),=臂]<DG + 心),= 臂]<DG) The tran sfer fun cti on of an gle and positi on...
In the Laplace domain, Eq. (17.62) can be written in transfer function form as (17.63)Φ(s)=−6rs2Ls2−3gω(s). The DC motor model can be used directly to eliminate ω(s) and obtain the transfer function between the motor current, that is, the corrective action, and the ...
Objective: The aim of our study is to explore the role of Tanshinone IIA (Tan IIA) in the apoptosis of epidermal HaCaT cells induced by H2O2, with a focus on mitochondrial homeostasis and inverted formin-2 (INF2). Materials and methods: Cellular viability was determined using the MTT assay...
For example, by simply replicating D times the 2D index may improve the throughput roughly in a linear way as a function of the number of replicas, because the D sets of processors form D independent 2D index. Then each single 2D index replica processes a different set of queries. No ...