which does not take into account the accepted range of biological behavior of breast carcinomas. Bloom and Richardson observed at that time that clinical staging provided a useful guide, yet “it fails completely to indicate the likelihood of occult lymphatic and blood-born metastases being ...
A histopathological image dataset for grading breast invasive ductal carcinomas Original Data In this dataset, a histopathological microscopy image dataset of 922 images related to 124 patients with IDC is introduced. This dataset is published and accessible through web via: http://databiox.com. What...
Grade 1 invasive ductal carcinoma cells, which are sometimes called “well differentiated,” look and act somewhat like healthy breast cells. Grade 3 cells, also called“poorly differentiated,” are more abnormal in their behavior and appearance. Can invasive ductal carcinoma come back? Invasive duct...
25–60% DCIS progress to invasive ductal carcinoma (IDC). The challenge lies in distinguishing between non-progressive and progressive DCIS, often resulting in over- or under-treatment in many cases. With increasing screen-detected DCIS in these years, the nature of DCIS has aroused worldwide...
We studied by array-CGH a group of 57 invasive ductal carcinomas of the breast to outline the DNA copy number aberration (CNA) profile linked to high histologic grades and LVI. Selected CNAs were validated using real-time quantitative PCR (qPCR). Furthermore, gene expression analysis was ...
tissue images from invasive ductal carcinoma (T) and/or from healthy breast tissue (G); b) tumor grades 1-3 [16]; c) pathologic axillary nodal status; d) present lymphangiosis [16]; e) estrogen receptor (ER), immunoreactive score: 0- 12 [17]; f) progesterone receptor (PR), immunor...
Thus, we investigated immunohistochemically the levels of APC7 in various cancer tissues and found weak APC7 expression in high-grade ductal carcinomas of breast. Therefore, we were encouraged to investigate the expression of APC7 in 108 breast carcinomas and to examine the relationship between ...
Sixty-four tissue blocks were used in this study of which 34 (53.1%) were Invasive ductal carcinoma (IDC) (cases) and 30 (46.8%) were fibroadenomas (controls). Examination of Verhoeff's stained sections revealed different grades of elastosis in 29 (85.2%) cases compared to seven (23.3%)...
High TILs was more frequently found in invasive ductal carcinoma (252/720; 35.0%) than in invasive lobular carcinoma (3/16; 18.8%; P = 0.0039). Similarly, high TILs was more common in TNBC (56/113; 49.6%) and HER2+ carcinomas (101/264; 38.3%) than in HR+HER2− cancer (...
Invasive ductal carcinomas (IDCs), a group of heterogeneous tumors that lack themorphological characteristicsthat would allow them to be classified as any specific histological types, account for up to 80% of all invasive breast cancers (Figure 1(a)). A tumor is classified asIDCNOS if the spec...