Adenocarcinoma in situ (AIS) is a pre-invasive lesion in the lung and a subtype of lung adenocarcinoma. The patients with AIS can be cured by resecting the lesion completely. In contrast, the patients with invasive lung adenocarcinoma have very poor 5-year survival rate. AIS can develop ...
In the new classification of lung adenocarcinoma introduced in 2011, the disease-related survival rate of patients with MIA lesions is close or equal to 100% provided the patient undergoes complete surgical resection. It is therefore extremely important to accurately distinguish between pre-invasive ...
In the genome era, the achievement of a safe and complete resection of oral cancers remains a challenge for surgeons. Margin length at histopathological examination is still considered the main indicator of oncological radicality. However, this parameter is fraught by major limitations. Cancer aggressiv...
Finally, the patient was diagnosed with pulmonary invasive mucinous adenocarcinoma and agreed to undergo a thoracoscopic surgery. Conclusions Pulmonary invasive mucinous adenocarcinoma is a subset of lung adenocarcinoma with low incidence rate. The clinical features and CT findings are non-specific. A ...
Is sub-lobular resection feasible for these early-stage lung cancer without lymph node metastasis? By analyzing patients with stage I peripheral lung adenocarcinoma, we found that if divide tumor into pre-invasive adenocarcinoma and invasive adenocarcinoma, the 5-year recurrence-free survival rate of ...
High level of tumor-infiltrating lymphocytes (TILs) can predict the rate of total pathological complete remission (tpCR) of breast cancer patients who receive neoadjuvant chemotherapy (NACT). This study focused on evaluating the data of patients whose primary tumor and/or lymph node metastasis show...
Invasive size is an independent predictor of survival in pulmonary adenocarcinoma. Am J Surg Pathol. 2009;33(3):462–9. Article PubMed PubMed Central Google Scholar Maeshima AM, et al. Histological scoring for small lung adenocarcinomas 2 cm or less in diameter: a reliable prognostic ...
Pleural deformation is associated with the invasiveness of lung adenocarcinoma(LAC). Our study focused on the pathological components of the area adjacent pleura in pulmonary pure ground-glass nodules(pGGNs) with pleural deformations(P-pGGNs) confirmed t
The cell ecology and spatial niche implicated in the dynamic and sequential process of lung adenocarcinoma (LUAD) from adenocarcinoma in situ (AIS) to minimally invasive adenocarcinoma (MIA) and subsequent invasive adenocarcinoma (IAC) have not yet been
Several studies have provided some initial supporting evidence; for example, high subclonal mutations in primary lung adenocarcinoma patients were correlated with high relapse rate39 and genomic characteristics of metastatic/relapsed lesions that have a similar patterns as subclones of primary tumors40,4...