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In this work, we set out to determine ACE2 interaction with NHERF1 and their critical interacting structural determinants and further evaluate the functional definition of NHERF1 in ACE2-mediated SARS-CoV-2 entry. Our results confirm that NHERF1 binds to the C-terminal tail of ACE2 through...
the truth of the matter is that many enterprises and government agencies still question the privacy and security of public cloud services. "this level of control is very important in regulated industries: financial services and healthcare," says michael r. overly, a lawyer with the international ...
CT imaging was acquired by one of these two CT scanners (256-detector row, Brilliance, Philips Medical Systems, Netherlands; 64 slices dual source, Definition, Siemens Medical Systems). The protocol parameters of these two scanners were as follows: tube current = 250 mA; tube voltage =...
To facilitate intercellular communication, cells release nano-sized, extracellular vesicles (EVs) to transfer biological cargo to both local and distant sites. EVs are enriched in tetraspanins, two of which (CD9 and CD151) have altered expression pattern
Informed consent was obtained from all subjects involved in the study. Data Availability Statement Data are available on request due to restrictions (privacy and ethical). Conflicts of Interest The authors declare no conflict of interest. Appendix A Figure A1. Adjusted Kaplan–Meier curves for bioch...