We therefore report on the favourable prognosis of our AML with inv(16) or variants.doi:10.1007/978-3-642-78350-0_108I. Plantier-ColcherJ. L. LaiC. PreudhommeN. Cambier-LotP. Fenaux
Acute myeloid leukemias (AMLs) carrying inv(16)/t(16;16) chromosomal abnormalities are associated with a good prognosis. However, studies of this AML subtype have been hampered by the few number of patients reported, frequently collectively considered with those with AML carrying the t(8;21) ...
Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup. Blood 2003; 102: 462–469. Article CAS Google Scholar Download references Acknowledgements This investigation was performed in part in the Laboratory for Leukemia Diagnostics; ...
Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood, 100 (2002), pp. 59-66 View PDFView articleView in Scopus...
prognosis, shorter OS and DFS thanthose younger than 45 years old.Conclusion:Advanced age(optimal cutpoint, 45 years)was the major poor factorfor AML with inv(16)/ t(16;16).Key words leukemia;acute;myeloid;chromosome;therapy;outcome Inv(16)/t(16 ;16)为急性髓系白血病(acutemyeloblastic ...
( AML) has received emphasis.Of C— KIT mutations, 8 exon mutation( mutKIT 8 ) and 17 exon mutation ( mutKIT 17 ) were the focuses of research, which were common in AML with t( 8 ; 2 1) or inv( 16) and associated with the clinical prognosis Amount of researches in our country...
RUNX1 mutations are frequent in de novo AML with noncomplex karyotype and confer an unfavorable prognosis Blood, 117 (2011), pp. 2348-2357 View PDFView articleCrossrefView in ScopusGoogle Scholar Speck and Gilliland, 2002 N.A. Speck, D.G. Gilliland Core-binding factors in haematopoiesis and...
1- t(16;16)(p13;q22); - del(16)(q22): may be associated with less typical phenotype and preceding MDS, older age, complex karyotype, worse prognosis; 2- but also: translocations of 16q22 with various partners in: t(1;16)(p31-32;q22), t(3;16)(q21;q22), inv(16)(p13...
目的探讨DNA同源重组修复基因RAD51-G135C和XRCC3-C241T多态性与inv(16)/t(16;16)/CBFβ-MYH11阳性急性髓系白血病(AML)患者预后之间的关系。方法对染色体核型可供分析且随访资料完整的103例初治原发性inv(16)/t(16;16)/CBFβ-MYH11阳性AML患者进行回顾性分析。用聚合酶链反应-限制性片段长度多态性(PCR—...
None of the samples from the AML-M4 patients with inv(16) had detectable CEBPA protein. Eleven patients with AML-M4 and normal karyotypes were tested, with 6 having high expression as shown in the first lane of the 2 panels, 3 having weak CEBPA expression, and 2 having no detectable ...