Injections, IntravenousTHE intravenous injection of neonatal rats and mice is an exacting procedure; any refinement of technique which permits a safer, more reliable and more accurately measured infusion should be of value. In this laboratory a method has been evolved which has some of these ...
In addition, the following changes in laboratory parameters may identify a TMA complication: occurrence of two, or repeated measurement of any one of the following: a decrease in platelet count by 25% or more compared to baseline or the peak platelet count during Soliris treatment; an increase ...
In late 1974 and early 1975, several cases of viral hepatitis were reported in Italy among subjects who had received subcutaneous injections of a drug cont... PF Luigi,C Pietro,De Flora Silvio - 《Journal of Infectious Diseases》 被引量: 58发表: 1977年 加载更多来源...
routes. Embryonic day 14 B6 mice were injected with 5 × 106 B6GFP BM cells. PB donor cell engraftment was analyzed at 1, 2, 3, and 6 months of age (A). Engraftment levels were further analyzed to determine the percentage increase in chimerism achieved by the i.v. route of injection...
AAV.CAP-B10 is significantly targeted away from Purkinje cells in the cerebellum. ssAAV-PHP.eB:CAG-NLSx2-EGFP and ssAAV.CAP-B10:CAG-NLSx2-EGFP were intravenously injected into male adult mice at 1 × 1011vg/mouse. GFP fluorescence was assessed after three weeks of expression. (a, ...
While mechanisms like saturation of neonatal Fc receptor (FcRn), neutralization of pathogenic autoantibodies and inflammatory cytokines, and complement scavenging are functioning during early phase of IVIG therapy; regulation of immune cells like innate cells (like DCs, neutrophils, monocytes, macrophages,...
While highly sialylated IgG glycovariants were essential for IVIg activity, it was independent of the Fc-receptor genotype and did not result in a general block of activating or the neonatal Fc-receptor. These findings may help in the development of strategies to block autoantibody and enhance ...
Fetal/Neonatal Adverse Reactions Because ustekinumab products may theoretically interfere with immune response to infections, consider risks and benefits prior to administering live vaccines to infants exposed to IMULDOSA in utero. There are insufficient data regarding exposed infant serum levels of ustekinum...
ELOCTATE is a recombinant fusion protein that temporarily replaces the missing Coagulation Factor VIII needed for effective hemostasis. ELOCTATE contains the Fc region of human immunoglobulin G1 (IgG1), which binds to the neonatal Fc receptor (FcRn). FcRn is part of a naturally occurring pathway ...
Neonatal intraperitoneal or intravenous injections of recombinant adeno-associated virus type 8 transduce dorsal root ganglia and lower motor neurons. Hum Genet Ther. 2008; 19 :61–70. [ PubMed ]Foust KD, Poirier A, Pacak CA, Mandel RJ, Flotte TR. Neonatal intraperitoneal or intravenous ...