Changes of intraocular pressure after intravitreal injection of bevacizumab (Avastin). Retina 2007; 27(8): 1044–7Falkenstein IA, Cheng L, Freeman WR. Changes of intraocular pressure after intravitreal injection of bevacizumab (avastin) Retin-J Retin Vitr Dis. 2007; 27 :1044–1047....
15. Obviously, if a fluid is injected into the eye the intraocular pressure (IOP) should increase. Therefore immediately after the administration of an intravitreal injection, acute fluctuations of the IOP will be present; which
The use of intraocular injection of corticosteroids bypasses all potential barriers and produces a very high concentration of the corticosteroid in the intraocular compartment. Also anti-VEGF drugs like Avastin can be injected into the vitreous. The effect of all injections is short-live and repeated...
Pharmacokinetics of intravitreal bevacizumab (Avastin(R)) in rabbits. Clin Ophthalmol 2011; 5: 697–704. Article CAS Google Scholar Kim H, Csaky KG, Chan CC, Bungay PM, Lutz RJ, Dedrick RL et al. The pharmacokinetics of rituximab following an intravitreal injection. Exp Eye Res 2006; 82:...
Also, there was an increased odds ratio (16.1, P = 0.008) of sustained IOP elevation in eyes receiving ≥29 injections compared with ≤12 injections. After controlling for the confounder (prior intravitreal steroid injection), total number of injections still showed a statistically significant ...
Christoforidis, J. B., Carlton, M. M., Knopp, M. V., Hinkle, G. H.PET/CT imaging of I-124-radiolabeled bevacizumab and ranibizumab after intravitreal injection in a rabbit model.Invest Ophthalmol Vis Sci.52, 5899-5903 (2011). ...
“Implant,” as generally used herein, refers to a polymeric device or element that is structured, sized, or otherwise configured to be implanted, preferably by injection or surgical implantation, in a specific region of the body so as to provide therapeutic benefit by releasing an active agent...
vascular endothelial cells, and enhanced retinal neovascularization after intraocular injection of an adenoviral vector containing an annexin A2 expression cassette... SH Zhao,LN Huang,JH Wu,... - 《Molecular Vision》 被引量: 88发表: 2009年 Effect of subconjunctival and intraocular bevacizumab inject...
Acute intraocular inflammation following intravitreal injection of bevacizumab – a large cluster of casesdoi:10.1111/j.1755-3768.2010.02054.xEditors, Intravitreal bevacizumab (Avastin, F. Hoffman – La Roche Ltd.) has frequently been associated with sterile intraocular inflammation. Although the exact ...
Several reports addressed the possible elevation of intraocular pressure (IOP) following intravitreal injection of anti-VEGF. The aim of this study was to determine the prevalence of sustained IOP elevation following intravitreal bevacizumab injections for neovascular AMD and identify possible risk factors ...