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indicating GC-like properties of this cell line. Second, much higher OATP2B1 mRNA and protein levels were detected in long-term Caco-2 cultures compared with the intestinal epithelium, again consistent with other studies [5,39]. Third, as recently reported, Caco-2 cells showed low PXR-and ...
In the present study, we used a 2-day administration condition to examine short-term effects, but in our previous study, we observed a marked recovery of small intestinal function after 3 days of administration. Therefore, it is suggested that even small doses can promote significant activation...
AKG did not alter body weight gain in operated rats (Figure 1), which would be an important issue with long-term supplementation in practice. Although many of the beneficial metabolic effects of bariatric surgery can be attributed to weight loss, the rapid changes in most gut hormones, ...