Szych J, Wolkowicz T, La Ragione R, Madajczak G. Impact of antibiotics on the intestinal microbiota and on the treatment of Shiga-toxin-producing Escherichia coli and Salmonella infections. Curr Pharm Des. 2014;20:4535-48.Jolanta Szych,Tomasz Wolkowicz,Roberto La Ragione,Grzegorz Madajczak....
The microbiome modulates host immunity and aids the maintenance of tolerance in the gut, where microbial and food-derived antigens are abundant. Yet modern dietary factors and the excessive use of antibiotics have contributed to the rising incidence of food allergies, inflammatory bowel disease and o...
Can diet be used as an alternative to antibiotics to help control enteric bacterial infections of pigs? In the case of the related intestinal spirochaete Brachyspira (Serpulina) pilosicoli, the aetiological agent of porcine intestinal spirochaetosis, feeding ... DJ Hampson,DW Pethick,JR Pluske...
and more serious than that in western countries,which means the problem of bacterial resistance trouble the medical personnel in the whole world.The correct use of antibiotics can not only ensure the effect of anti-infective therapy,but also to reduce the adverse reactions and delay the occurrence...
Just as a healthy microbiota promotes neuron–MM interactions, microbial dysbiosis can negatively impact neuro-immune crosstalk. For example, enteric infection-induced loss of enteric neurons is directly dependent on microbial dysbiosis resulting from infection.31Treatment with antibiotics following pathogen ...
(scale bar, left). Multiple factors influence initial development of the gut microbiota, while diet has long-term impact on community maintenance. Exposure to exogenous factors such as antibiotics eliminate commensal organisms and allow expansion of the resistant population including pathobionts. ...
Antibiotic treatment disrupts the native intestinal microbiota and favours infection with and the proliferation of antibiotic-resistant intestinal pathogens. Clinically important antibiotic-resistant pathogens include vancomycin-resistant Enterococcus spp., various Enterobacteriaceae and Clostridium difficile. The intes...
A Randomized Placebo-Controlled Trial of Saccharomyces boulardii in Combination With Standard Antibiotics for Clostridium difficile Disease The treatment combines the yeast Saccharomyces boulardii with an antibiotic (vancomycin hydrochloride or metronidazole). DESIGN--A double-blind, randomized, ... LV Mc...
Antibiotics for Treatment of Acute Respiratory Tract Infections: Decreasing Benefit, Increasing Risk, and the Irrelevance of Antimicrobial Resistance Despite little microbiological reason indicating that it would be helpful, antibiotic prescribing for treatment of predominantly viral acute respiratory tr... JA...
5c). Importantly, these striking systemic immune changes were not a result of systemic fungal infection as fungal cultures of the kidneys, a classic marker of fungemia32, were negative in all mice. Fig. 5: Fungal colonization alters early-life systemic immunity in mice. Percentage of a ...