Chace, Donald HChace DH. Method for interpreting tandem mass spectrometry data for clinical diagnosis. US Patent No. 6,455,321 B1, September 24, 2002.
Buprenorphine urine testing can be performed using immunoassay (IA), gas chromatography-mass spectrometry (GC–MS), and liquid chromatography-tandem mass spectrometry (LC–MS/MS) assays. GC–MS and LC–MS/MS can quantify the concentration of buprenorphine and its metabolites in the urine and gener...
Method for interpreting tandem mass spectrometry d 专利内容由知识产权出版社提供 专利名称:Method for interpreting tandem mass spectrometry data for clinical diagnosis 发明人:Donald H. Chace 申请号:US1122524 3 申请日:20050913 公开号:US20060128027A1 公开日:20060615 摘要:A method for interpreting data ...
We introduce Decomp, a tool that computes the sum formula of all molecules whose mass equals the input mass. This problem arises frequently in biochemistry and mass spectrometry (MS), when we know the molecular mass of a protein, DNA or metabolite fragment but have no other information. A cl...
RATIONALE Soft ionization, high-resolution mass spectrometry is widely used to characterize large biological molecules, such as proteins. Deconvolution ('deisotoping') of isotopic envelopes (iEs) in biological mass spectra into monoisotopic or average masses is challenging due to low signals and heavil...
We introduce PHOXTRACK (PHOsphosite-X-TRacing Analysis of Causal Kinases), a user-friendly freely available software tool for analyzing large datasets of post-translational modifications of proteins, such as phosphorylation, which are commonly gained by mass spectrometry detection. In contrast to other...
Once these problems are solved, the use of artificial intelligence in data driven systems biology through the integration of multi-omics will be a key next step in solving the genotype-phenotype problem. Conclusions The remarkable advances in imaging, sequencing, and mass spectrometry technologies ...
13.7 Spin-Spin Splitting in 1H NMR Spectroscopy Not all peaks are singlets. Signals can be split by coupling of nuclear spins. 12 Figure 13.13 Cl2CHCH3 4 lines; quartet 2 lines; doublet CH3 CH 1.0 2.0 3.0 4.0 5.0 6.0 7.0 8.0 9.0 10.0 Chemical shift (, ppm) 1 ...
High-performance liquid chromatography-electrospray ionization tandem mass spectrometry for metabolism study of timosaponin AIII. J Chromatogr Sci. 2014;52:418–22. Article CAS PubMed Google Scholar Tian X, Gao Y, Xu Z, Lian S, Ma Y, Guo X, et al. Pharmacokinetics of mangiferin and its ...
A method for interpreting data that is produced after a group of amino acids and acylcarnitines are derivatized from blood spots taken from newborn babies and scanned by a tandem mass spectrometer. Co