Although there is no standard definition, polypharmacy is generally defined as the concurrent use of five or more medications [51], over-the-counter and complementary medicines included. It increases MEs because it reduces compliance and favors timing and/or dosing errors, duplications, or omissions....
EMA indicates European Medicines Agency; FDA, US Food and Drug Administration; NHS, National Health Service; and NICE, National Institute for Health and Care Excellence. Figure 2. Timeline of Evidence for Accelerated Approval Cancer Drug Appraisals From the FDA, EMA, and NICE View LargeDownload ...
ImportanceAnticholinergic medicines have short-term cognitive adverse effects, but it is uncertain whether long-term use of these drugs is associated with an increased risk of dementia. ObjectiveTo assess associations between anticholinergic drug treatments and risk of dementia in persons 55 years or old...
Internal & Emergency MedicineSaddichha S, Saxena MK. Is every chest pain a cardiac event?: An audit of patients with chest pain presenting to emergency... S Saddichha,MK Saxena - 《Internal & Emergency Medicine》 被引量: 8发表: 2009年 An audit to review compliance to cisplatin hydration...
Finally, older patients are under-represented in medical research, even for pathologies or medicines most relevant to their age group16,17,18. As CSDH occurs almost exclusively in older patients, we aimed to demonstrate that the barriers to trial recruitment and follow-up can be overcome. Members...