mortality rate with the dynamic changes of IL-6 was significant(P for trend = 0.023).CONCLUSION A high level of serum IL-6 is an independent risk factor for mortality in patients with HBV-ACLF.Furthermore,a sustained high level or dynamic elevated level of serum IL-6 indicates a higher ...
Absorption of the anti-recombinant IL-6 antisera with purified fibroblast-derived IL-6 or with recombinant IL-6, but not bovine serum albumin, removed the immunostaining. Increased levels of IL-6 were detected in the plasma of patients with active psoriasis (mean 3 ng/ml) by using two ...
Evaluation of serum high-sensitivity C-reactive protein level and white blood cell count on risk for coronary heart disease; 超敏C反应蛋白及白细胞计数对冠心病的评估价值 3. Relationship between C-reactive protein and white blood cell in chidren with acute bacterial infection; ...
Interleukin-6 IL-6 is a pro-inflammatory cytokine, and a higher level of serum IL-6 was found inPCOSpatients[49,50]. Its promoter regionSNPrs1800795 (−174 C/G) has been suggested to be associated with PCOS[51,52], but the results from other studies were opposite. For example, two...
Interleukin-6 (IL-6) is a potent immunomodulatory cytokine that may have pathogenetic and prognostic significance in a number of disorders. The objective of this study was to examine the correlation between serum IL-6 levels and phenotypic characteristics, as well as failure-free survival of patien...
Increased levels of IL-6 were found to be significantly associated with adverse clinical COVID-19 outcomes such as ICU admission, acute respiratory distress syndrome (ARDS), and death. In addition, patients with such complicated forms of COVID-19 had nearly threefold higher serum IL-6 levels ...
The same study already provided evidence that extracellular, soluble IL-6R (sIL-6R) in the presence of IL-6 could activate cells expressing gp130, and stated that naturally occurring sIL-6R could be found in the murine serum. It is now widely accepted that sIL-6R is formed physiologically,...
Box-and-whisker-plots extending down to the minimum value and up to the maximum level of RMI score, ROMA, serum levels of CA125, HE4, IL-6 and IL-8 in patients with high-grade serous EOC, with benign ovarian masses and normal ovaries. The p-value is indicated for each factor. ...
Elevated serum levels of interleukin-6, interleukin-1beta and human chorionic gonadotropin in pre-eclampsia. Am J Reprod Immunol 2011;66: 468-75.Peraçoli JC, Bannwart-Castro CF, Romao M, Weel IC, Ribeiro VR, Borges VT, et al. High levels of heat shock protein 70 are associated with ...
In addition, several studies have documented significant associations between poor OCCC prognosis and high IL-6 in tumor or serum samples5,11,20. Anglesio et al. reported upregulation of the IL-6/STAT3/HIF pathway and therapeutic responses to the anti-angiogenic agent sunitinib in two ...