Interleukin-31 does not induce immediate itch in atopic dermatitis patients and healthy controls after skin challenge. Allergy 69: 113-117.Hawro, T., et al., Interleukin-31 does not induce immediate itch in atopic dermatitis patients and healthy controls after skin challenge. Allergy, 2013. 20...
pruritic symptomspsoriasisseverityInterleukin-31 (IL-31) is one of the main cytokines that cause pruritus in a variety of skin conditions. Also, immunoglobulin E (IgE) is one type of immunoglobulin that is necessary for the allergic reaction. There is some evidence to suggest that IgE and IL-...
Transfer of cDC2s isolated from late-stage wounds into healthy skin was sufficient to induce itching in a manner dependent on IL-31 expression. Addition of the cytokine TGF-β1, which promotes wound healing, to dermal DCs in vitro was sufficient to induce Il31 expression, and Tgfbr1f/f ...
Atopic dermatitis (AD), also known as atopic eczema, is a chronic inflammatory skin disease that causes intense itching and recurrent eczematous lesions [1]. Characterized by debilitating signs and symptoms—intense itching (pruritus), eczematous lesions, and impaired skin barrier—AD disrupts physical...
Atopic dermatitis (AD) is a pruritic disease of unknown origin that usually starts in early infancy (an adult-onset variant is recognized); it is characterized by pruritus, eczematous lesions, xerosis (dry skin), and lichenification (thickening of the sk
Here we report that Tg mice expressing IL-4 in the skin developed a chronic, inflammatory, pruritic skin disease associated with bacterial infection and that the mouse disease phenotype is clinically, microbiologically, pathologically, and serologically identical to AD in humans and fulfills the ...
“Atopic dermatitis” (or neuro dermatitis) is an inflammatory, chronically relapsing, non-contagious and pruritic skin disorder. The skin of a patient with atopic dermatitis reacts abnormally and easily to irritants, food, and environmental allergens and becomes red, flaky and very itchy. It also...
In order to cross intact mammalian skin, lipid vesicles must pass through a series of fine pores, each with a diameter less than 50 nm, under the influence of a suitable transdermal gradient. Therefore, it is desirable to use a liposome which is highly deformable and able to pass through ...
Serum IL-31 level is an objective reliable marker of AD severity in children. It may represent a novel target for antipruritic drug development.doi:10.1111/j.1468-3083.2010.03794.xM H M EzzatZ.E. HasanK Y A ShaheenBlackwell Publishing LtdJournal of the European Academy of Dermatology and ...
IL‐31, TSLP and MCP‐1 levels were upregulated in pruritic, alopecic skin lesions compared to healthy skin of the same horse. Clinical signs and pruritic behaviour improved in all four horses upon vaccination with eIL‐31‐CuMV TT vaccine. The vaccine was well tolerated without safety ...