Interleukin-6Body FluidsWe report on the levels of expression of IL-1 and IL-6 in skin from psoriasis patients. Different approaches were pursued. Initially, the levels of IL-1 beta and IL-6 were measured in suction blister fluid from lesional and uninvolved skin from psoriasis patients, ...
Interleukin-1, interleukin-6 and the germ cell-Sertoli cell cross-talk. Jégou,Cudicini,Gomez,... - 《Reproduction Fertility & Development》 被引量: 74发表: 1995年 Human Leydig cells and Sertoli cells are producers of interleukins-1 and -6. Interleukins (IL)-1 and -6 have been shown ...
Our purpose was to investigate the cytokines, tumor necrosis factor, interleukin-1, and interleukin-6 in normal human pregnancy and labor. Bioassays were used to measure these factors in extraembryonic coelomic fluid, amniotic fluid, placenta, and maternal and cord serum. Little or no tumor necrosi...
the differentiation of TH-17 cells requires transforming growth factor-β and IL-6 and the transcription factor RORγt. We report here that for human naive CD4+T cells, RORγt expression and TH-17 polarization were induced by IL-1β and ...
Tumor necrosis factor alpha, interleukin-1 alpha, interleukin-6, and prostaglandin E2 production in murine peritoneal macrophages infected with Ehrlichia r... Ehrlichia risticii is a gram-negative obligate intracellular bacterium which primarily infects macrophages and crypt epithelial cells in the intesti...
As proinflammatory cytokines, including interleukin-6 (IL-6) and the interleukin-1 (IL-1) family, seem to contribute to the pathogenesis of JSLE, this investigation was performed to assess the associations of particular single nucleotide polymorphisms ( SNPs ) of IL-6 and IL-1 genes in a ...
Increased IL-6 could signal the involvement of antiinflammatory activity, since IL-6 stimulates the production of endogenous antiinflammatory mediators such as interleukin-1 receptor antagonist (IL-1RA). To better understand the interaction of pro- and antiinflammatory acute phase processes in brain ...
Interleukin 6is a 25-kDa glycoprotein that is produced by macrophages,endothelial cells,vascular smooth muscle cells, and endometrial epithelial andstromal cells[28,29]. Like IL-1, IL-6 modulates secretion of other cytokines, promotes T-cell activation and B-cell differentiation, and inhibits growt...
The aim of this study was to investigate the involvement of the monocyte-derived cytokines interleukin 1β (IL-1β), interleukin 6 (IL-6) and tumour necrosis factor-α (TNF-α) in idiopathic inflammatory bowel disease. Endoscopic biopsies of normal and inflamed intestinal mucosa were obtained ...
The Toll–Interleukin-1 Receptor Member SIGIRR Regulates Colonic Epithelial Homeostasis, Inflammation, and Tumorigenesis Author links open overlay panelHui Xiao 1 6, Muhammet Fatih Gulen 1 2 6, Jinzhong Qin 1 2 6, Jianhong Yao 1, Katarzyna Bulek 1, Danielle Kish 1, Cengiz Zubeyir Altuntas 1,...