Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity.doi:10.1038/cddis.2017.67Interferon gamma (IFNγ) is a key moderator of cell-mediated immunity with diverse, mainly pro-inflammatory actions on immunocytes and target tissue. Recent studies have shown it ...
from cytotoxic lymphocytes directly enhances their motility and cytotoxicity Purnima Bhat*,1,2, Graham Leggatt1, Nigel Waterhouse3 and Ian H Frazer1 Interferon gamma (IFNγ) is a key moderator of cell-mediated immunity with diverse, mainly pro-inflammatory actions on immunocytes and target ...
PREPARATION OF INTERFERON-GAMMA HuIFN-gamma is derived from human myelomonocyte cell lines. Monoclonal anti-HuIFN-gamma antibodies are prepared using the HuIFN-gamma and are used to purify HuIFN-gamma. HuIFN-gamma is effective in preventing and treating viral diseases,... MASASHI * KURIMOTO,MAS...
Taken together, these data demonstrate that soluble factors, or products derived from MSC, modulate immune responses and suggest that MSC create an immunosuppressive microenvironment capable of modulating alloresponsiveness even in the presence of IFN-gamma. 展开 ...
内容提示: Page 1 of 2 Non WHO Reference Material INTERFERON GAMMA (HUMAN, rDNA derived) NIBSC code: 87/586 Instructions for use (Version 7.0, Dated 19/04/2013) This material is not for in vitro diagnostic use. 1. INTENDED USE As a biological reference standard for Interferon Gamma 2. ...
The same maneuver is also able to reduce by approximately 50-70% the surface expression of two IFN-gamma-induced immunoregulatory molecules: HLA-DR and ICAM-1. These results demonstrate that the JAK2 and Stat1 signalling pathway is active in salivary-derived epithelial cells and may contribute to...
TNFRSF14 is an IC closely relevant to IFN signaling activation in GBM To screen the ICs associated with IFN signaling activation in GBM, we firstly summarized a list of 67 ICs encoding genes (Table S4). According to HALLMARK INTERFERON ALPHA RESPONSE and HALLMARK INTERFERON GAMMA RESPONSE gene ...
(IFNW). TheType II IFNclass is represented by a single member, termed IFN gamma (IFNG), and theType III IFNclass contains at least three members that are known either as IFN lambda (IFNL) 1, 2, and 3 or as interleukin (IL) 29, 28A, and 28B. The roles of IFN are perhaps best...
Interferon gamma stimulates beta-secretase expression and sAPPbeta production in astrocytes Biochem Biophys Res Commun, 307 (2003), pp. 922-927 View PDFView articleView in ScopusGoogle Scholar 48 Q Yan, J Zhang, H Liu, S Babu-Khan, R Vassar, AL Biere, M Citron, G Landreth Anti-inflammato...
Moreover, the effective inhibition of host-reactive donor T cell activation and expansion that is associated with IL-12-mediated GVHD protection was dependent on the ability of BALB/c donors to produce IFN-gamma. These results demonstrate that (a) acute GVHD can be induced in the absence of ...