Hepatitis-C, treatmentInterferon, therapeutic useMeta-analysisPeginterferon-alfa-2a, therapeutic usePeginterferon-alfa-2b, therapeutic useQuality-of-lifeRibavirin, therapeutic useThe article discusses research being done on the efficacy of peginterferon plus ribavirin in the treatment of hepatitis C. It ...
Hepatitis C virus (HCV) is a more important factor associated with hepatocellular carcinoma than hepatitis B virus (HBV) in Japan and certain Western countries [1–3]. Some patients who contracted chronic non-A, non-B hepatitis after blood transfusion an
Interferon-free therapy for hep C Dorey, Emma - Chemistry & Industry 被引量: 0发表: 2012年 Interferon-alpha therapy for hepatitis C virus infection after liver transplantation. The aims of this pilot study were to evaluate the safety and efficacy of interferon-alpha 2b for treatment of in ...
Risk factors for hepatocellular carcinoma and its incidence after interferon treatment in patients with chronic hepatitis C (p1394-1402) However, the degree of fibrosis was not a significant risk factor for the development of HCC (risk ratio, 3.16; P = .052). These results suggest that patients...
(Applied Biosystems, Carlsbad, USA) and enzymes were inactivated at 95 °C for 20 s. Biotinylated cDNA was purified with the MinElute PCR Purification Kit (Qiagen, Hilden, Germany) and isolated with dynabeads specifically interacting with biotin (Dynal Kilobase Binder Kit, Invitrogen, ...
Model for the chain terminating mechanism of 2'-methyl nucleosides. This growing chain model was generated by attaching double-stranded RNA to the first two G:C base pairs found in the phi6 phage RNA polymerase (PDB: 1hi1) and energy minimization of the junction. The template strand is ...
New treatments for chronic hepatitis C:an overview for paediatricians Pegylated interferon(IFN)伪-2a or 2b in combination with ribavirin for children aged 3 years and older is the standard treatment for paediatric chronic hep... D Serranti,G Indolfi,M Resti,... - 《World Journal of Gastroent...
Interferon was discovered when Isaacs and Lindenmann (1957) infected fragments of chick chorioallantoic membrane with heat-inactivated influenza virus. The viral component or components responsible for interferon induction were not identified then, and i
The article focuses on two studies that investigated the effectiveness of the albumin interferon-α fusion protein combined with ribavirin in treating patients with chronic hepatitis C virus infections. Differences in the dosages given to the patients are cited. The patients' tolerance for the regimen...
For untreated patients with hepatitis C virus (HCV), treatment with an oral nucleotide inhibitor of HCV polymerase, sofosbuvir, plus ribavirin seems effective for genotypes 1, 2, and 3; and the HCV NS3 protease inhibitor ABT-450, combined with low-dose ritonavir plus the nonnucleoside NS5B poly...