Interferon-alpha inducible protein 6 (IFI6) confers protection against ionizing radiation in skin cellsIonizing radiationRadiation-induced skin injuryIFI6ApoptosisHeat shock responseBackground: Radiation-induced skin injury is one of the main adverse effects and a dose-limiting factor of radiotherapy ...
Viral entry requires co-operative interactions of several host cell factors. Interferon (IFN) and the IFN-stimulated genes (ISGs) play a central role in antiviral responses against hepatitis C virus (HCV) infection. We examined the effect of interferon-α inducible protein 6 (IFI6) against HCV...
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Define interferon alfa-2a. interferon alfa-2a synonyms, interferon alfa-2a pronunciation, interferon alfa-2a translation, English dictionary definition of interferon alfa-2a. n. 1. An organism, cell, or virus in which genetic recombination has taken plac
and correlated with MHC class I expression in muscle fibers.26In addition, the major producer of type I interferon, plasmacytoid dendritic cells, and the interferon-inducible protein, MXA, were present in the muscle tissue of preferentially not only patients with anti-Jo-1 and anti-SSA autoantibo...
IL, interleukin; TNF, tumor necrosis factor; IP-10, interferon γ-induced protein 10; MCP-1, monocyte chemoattractant protein-1. Given the increased neutrophilic responses in the BAL by IFN-α gene transfer, we next assessed cytokine and chemokine levels in the BAL at 20 hours following S. ...
Identification of Residues Critical for Regulation of Protein Stability and the Transactivation Function of the Hypoxia-inducible Factor-1α by the von Hip... Under normoxic conditions the hypoxia-inducible factor-1alpha (HIF-1alpha) protein is targeted for degradation by the von Hippel-Lindau (pVHL...
VHL protein is the substrate recognition component of the E3 ligase that ubiquitinates hypoxia‑inducible transcription factors (HIFs), including HIF‑1α and ‑2α. VHL plays a pivotal role in the downregula- tion of VEGF expression (20). Previous studies have ind...
英文名:CXCL11 (TAC, SCYB11, SCYB9B, C-X-C Motif Chemokine 11, Beta-R1, H174, Interferon gamma-inducible Protein 9, Interferon-inducible T-cell alpha Chemoattractant, Small-inducible Cytokine B11) (HRP) 中文名: CBNumber:CB04974000 分子式: 分子量:0 MOL File:Mol file CXCL11 (TAC, SCYB...
ISG15 is part of a ubiquitin-like pathway that modulates the function of numerous protein targets. The Mx proteins seem to survey exocytic events and mediate vesicle trafficking to trap viral components. The OAS-regulated RNaseL pathway degrades single-stranded RNA in virus-infected cells. ...