Adjuvant activity of interferon alpha: mechanism(s) of action. Vaccine 24(Suppl. 2): S2-46-7.Tovey MG,Lallemand C,Meritet JF,et al.Adjuvant activity of interferon al- pha:mechanism(s) of action[J].Vaccine,2006,24(Suppl 2):2-46....
Mechanism of interferon action. Kinetics of induction of the antiviral state and protein phosphorylation in mouse fibroblasts treated with natural and cloned - Samuel, Knutson - 1982 () Citation Context ...ter, at which time their livers were processed exactly as described for the CTL-injected ...
Mechanism of ActionImmunostimulants; Interferon alpha stimulants Orphan Drug Status Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases. No New Molecular EntityNo Highest Development Phases ...
Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2 alpha protein kinase (PKR) expression in transfected mammalian cells The expression of a molecular cDNA clone (P1 KIN) of the human RNA-dependent P1/eIF-2伪 protein kinase (PKR) was examined in transfected monkey cells and...
benzyl alcohol>phenoxyethanol. This specific order exactly matched with that observed for the model protein Cyt c. These and previously published results on antibodies and other recombinant proteins suggest that the general mechanism by which APs induce protein aggregation may be independent of the ...
Type I interferons, constituting IFN-alpha and IFN-beta, were initially described for their ability to interfere with viral replication. IFN-alpha was the first cytokine to be cloned and used successfully as a therapeutic cytokine, although its mechanism of action remained largely elusive. Evidence ...
It has also been suggested that myeloma patients may benefit from the addition of IFN-alpha in induction therapy and/or as maintenance treatment. The mechanism behind IFNs antitumour action in myeloma is, however, highly unclear. This probably means that current treatment regimens including IFN ...
Here we will review the consolidate signal transducer and activator of transcription (STAT)-dependent mechanism of action of IFNα. We will discuss data obtained by us and others on the triggering of the stress-dependent kinase pathway induced by IFNα and its correlations with the apoptotic ...
The meaning of INTERFERON is any of a group of heat-stable soluble basic antiviral glycoprotein cytokines of low molecular weight that are produced by cells exposed usually to the action of a virus, sometimes to the action of another intracellular parasi
While the exact mechanism of action of interferon remains to be fully elucidated, it has been shown to cause osteoblastic differentiation. Because of successful treatment of other craniofacial tumors with interferon, we have treated patients with recurrent (aggressive) JOF by surgical enucleation with ...