James S. K. ShamJohns Hopkins Medical InstitutionsSpringer NetherlandsYip K-P, Balasubramanian L, Sham JSK (2011) Integrin-mediated mechanotransduction in vascu- lar smooth muscle cells. In: Kamkin A, Kiseleva I (eds) Mechanosensitivity in cells and tissues 4. Mechanosensitivity and ...
Importantly, integrins participate in keratinocyte mechanotransduction and could potentially regulate cell behavior within the altered mechanical microenvironment of a wound. While the complete functions of integrin receptors in cutaneous wound healing have yet to be determined, recent evidence suggests that ...
CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction. CD98hc (SLC3A2)loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction. ESTRACH S,LEE S A,BOULTER E,et al. ... Soline,Estrach,Sin-Ae,.....
Guo, R. Fässler Integrin-mediated mechanotransduction J. Cell Biol., 215 (2016), pp. 445-456 CrossrefView in ScopusGoogle Scholar 22 B. Wehrle-Haller Assembly and disassembly of cell matrix adhesions Curr. Opin. Cell Biol., 24 (2012), pp. 569-581 View PDFView articleView in Scopus...
Mechanotransduction and growth factor signalling to engineer cellular microenvironments Adv. Healthc. Mater., 6 (2017), p. 1700052,10.1002/adhm.201700052 Google Scholar 27 F. Diomede, S. Caputi, I. Merciaro, S. Frisone, C. D'Arcangelo, A. Piattelli, O. Trubiani ...
(Thbs1) as an extracellular mediator of matrix mechanotransduction that acts via integrin αvβ1 to establish focal adhesions and promotes nuclear shuttling of Yes-associated protein (YAP) in response to high strain of cyclic stretch. Thbs1-mediated YAP activation depends on the small GTPase Rap2...
Rab11b-mediated control of integrin β1 surface expression allows efficient engagement with the brain ECM, activating mechanotransduction signaling to promote survival. Lipophilic statins prevent membrane association and activity of Rab11b, and we provide proof-of principle that these drugs prevent breast ...
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Mechanotransduction via the nuclear envelope: a distant reflection of the cell surface Current Opinion in Cell Biology, Volume 44, 2017, pp. 59-67 Julien Aureille,…, Christophe Guilluy Mechanosensing dysregulation in the fibroblast: A hallmark of the aging heart Ageing Research Reviews, Volume 63...
Integrin signaling in cancer: Mechanotransduction, stemness, epithelial plasticity, and therapeutic resistance. Cancer Cell 2019, 35, 347–367. [Google Scholar] [CrossRef] [PubMed] Zhou, Z.; Qu, J.; He, L.; Peng, H.; Chen, P.; Zhou, Y. alpha6-Integrin alternative splicing: Distinct ...