alpha 2b beta 3 is flexed within the extracellular domains. Activation, either by intracellular signaling or by Mg2+or Mn2+binding, extends the integrin to expose the ligand binding site created by interaction of the beta 3 vWFA domain with the alpha 2b beta ‑propeller structure (1). The ...
产品名称:Integrin alpha 2b beta 3重组蛋白 种属 Mouse 表达系统 HEK293 标签 C-His 同用名 α2Bβ3; ITGA2B&ITGB3; ITGA2B; ITGB3 分子量 90-113 kDa 纯度 Greater than 95% as determined by reducing SDS-PAGE. 内毒素含量 <1 EU/μg, determined by LAL method. 蛋白磷酸酶1调节因子...
Human Integrin alpha 2B beta 3 (ITGA2B&ITGB3) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Leu32-Arg993(ITGA2B) acidic tail & GLy27-Asp718(ITGB3) basic tail.[Accession | P08514-1(ITGA2B)&P05106-1(ITGB3)]分子...
产品名称: Integrin alphaIIbbeta3 (GPIIb/IIIa, CD41/CD61) 产品型号: M023-2产品展商: Emfret产品文档: 无相关文档 简单介绍 M023-2 Integrin alphaIIbbeta3 (GPIIb/IIIa, CD41/CD61) JON/A Rat IgG2b PE FC (activ. form) 1.5 ml; 300 testsIntegrin...
To further characterize alphaIIbbeta3-talin interaction, we found that alphaIIbbeta3 bound dose-dependently to talin fragments corresponding to the 47-kDa head or the 200-kDa tail domains of talin, indicating that an integrin-binding site is present in each domain. In addition, over-expression ...
血小板膜糖蛋白Ⅱb抗体(CD41/Integrin alpha 2b) 价 格 ¥980 起批量 ≥1支 最小起订1支 供货总量50支 发货地址浙江省温州市 建议售价¥980/支 更新日期 2025年05月07日 产品规格50ul 即时洽谈 立即询价 查看联系方式 收藏产品 发送留言 举报 VIP3年 温州科淼生物科技有限公司 企业认证: 备 营...
2b). Integrin αIIbβ3 surface expression was reduced on resting and activated Str−/− platelets as tested with several specific anti-αIIbβ3 antibodies (Fig. 2b; Supplemental Fig. 5bi–gi), however, the expression ratio on activated/resting platelets was comparable to controls (Fig. 2...
S. The platelet integrin alphaIIbbeta3 differentially interacts with fibrin versus fibrinogen. J. Biol. Chem. 291, 7858–7867 (2016). Article CAS PubMed PubMed Central Google Scholar Litvinov, R. I., Shuman, H., Bennett, J. S. & Weisel, J. W. Binding strength and activation state...
PTK2B/PYK2-mediated activation (PubMed:18587400). Alpha D beta 2, selectively binds ICAM-3 and does not appear to bind ICAM-1. In addition, a soluble form of alpha D beta 2 binds VCAM-1 with greater efficiency relative to ICAM-3. The I domain of alpha D contains a binding site for...
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